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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 5.45
Human Site: T435 Identified Species: 8.57
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 T435 D H G S L A L T P R P Q L E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 N433 D P G C L D L N L R P Q L E L
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 I435 D T R C S A L I P R P Q L E L
Rat Rattus norvegicus Q568Y2 489 52306 T435 D T K C S A L T P R P Q L E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 C421 P S S T T L A C R D Q T R A L
Frog Xenopus laevis Q6DE00 478 52667 Q424 D S D T S L V Q R N S K T A L
Zebra Danio Brachydanio rerio A4QN59 498 55134 L436 S E T S S L V L R N Q T L T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 T409 A V N D S L E T G G D P A S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 T421 G K V R V Q K T E E E K N G D
Sea Urchin Strong. purpuratus XP_786110 552 60545 R499 D A G A L V S R D E P L T V S
Poplar Tree Populus trichocarpa XP_002326199 496 54716 T433 V L A L A N A T E K A L K L Q
Maize Zea mays NP_001146073 514 56668 H457 A L S I Q N Q H N D A V L Y Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 A429 E T M T L V Q A A E K A L Q L
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 V434 D E P E F D V V R G R Y T S T
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 P530 S D K P D A P P R S S A L T L
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 66.6 N.A. 66.6 73.3 N.A. N.A. 6.6 13.3 13.3 N.A. 13.3 N.A. 6.6 26.6
P-Site Similarity: 100 N.A. N.A. 66.6 N.A. 66.6 73.3 N.A. N.A. 13.3 33.3 26.6 N.A. 13.3 N.A. 20 33.3
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 6.6 6.6 N.A. 20 6.6 20
P-Site Similarity: 13.3 6.6 N.A. 40 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 7 7 7 27 14 7 7 0 14 14 7 14 0 % A
% Cys: 0 0 0 20 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 47 7 7 7 7 14 0 0 7 14 7 0 0 0 7 % D
% Glu: 7 14 0 7 0 0 7 0 14 20 7 0 0 27 0 % E
% Phe: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 20 0 0 0 0 0 7 14 0 0 0 7 0 % G
% His: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 7 14 0 0 0 7 0 0 7 7 14 7 0 0 % K
% Leu: 0 14 0 7 27 27 27 7 7 0 0 14 54 7 60 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 14 0 7 7 14 0 0 7 0 0 % N
% Pro: 7 7 7 7 0 0 7 7 20 0 34 7 0 0 0 % P
% Gln: 0 0 0 0 7 7 14 7 0 0 14 27 0 7 14 % Q
% Arg: 0 0 7 7 0 0 0 7 34 27 7 0 7 0 0 % R
% Ser: 14 14 14 14 34 0 7 0 0 7 14 0 0 14 7 % S
% Thr: 0 20 7 20 7 0 0 34 0 0 0 14 20 14 7 % T
% Val: 7 7 7 0 7 14 20 7 0 0 0 7 0 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _