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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH2 All Species: 13.64
Human Site: T470 Identified Species: 21.43
UniProt: Q9BQC3 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQC3 NP_001375.2 489 52083 T470 R L G Q T P V T E A V S G R R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532611 487 51822 T468 R L G Q T T V T G A V S G R R
Cat Felis silvestris
Mouse Mus musculus Q9CR25 489 52346 K470 R L G Q T P V K E A V R G R R
Rat Rattus norvegicus Q568Y2 489 52306 K470 R L G Q T P V K E A V Q G R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI2 477 52145 S456 Q L G K T A V S K A V Q G R R
Frog Xenopus laevis Q6DE00 478 52667 V459 A L G Q T P V V K A V E G R K
Zebra Danio Brachydanio rerio A4QN59 498 55134 V471 K L G Q T P V V K A V K G Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650402 469 52077 D444 D R T W Q G L D P A L G Q T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09454 476 52936 A456 L N D G V S T A E D S T K M G
Sea Urchin Strong. purpuratus XP_786110 552 60545 T534 K L G E T P V T K A T E G R K
Poplar Tree Populus trichocarpa XP_002326199 496 54716 D468 T R S Y H G L D M H G D D S M
Maize Zea mays NP_001146073 514 56668 D492 E Y E G P V P D S V L V G R M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191522 491 54825 G464 F L N R V Y R G L E I N S E N
Baker's Yeast Sacchar. cerevisiae P32461 534 59757 T469 K Q L T T R H T A S G A V I K
Red Bread Mold Neurospora crassa Q7S5C0 602 65317 V565 L R T Q R T W V G L G T D F D
Conservation
Percent
Protein Identity: 100 N.A. N.A. 88.3 N.A. 83.6 84.8 N.A. N.A. 47.4 44.3 38.7 N.A. 29.6 N.A. 29.8 35.5
Protein Similarity: 100 N.A. N.A. 91.6 N.A. 88.9 89.5 N.A. N.A. 60.3 61.1 56.6 N.A. 47.6 N.A. 48.2 51.2
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 86.6 86.6 N.A. N.A. 60 66.6 66.6 N.A. 6.6 N.A. 6.6 60
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 86.6 86.6 N.A. N.A. 86.6 80 86.6 N.A. 20 N.A. 13.3 86.6
Percent
Protein Identity: 27 26 N.A. 26.2 25.6 24.7
Protein Similarity: 44.1 43.3 N.A. 45.2 40.8 37.2
P-Site Identity: 0 13.3 N.A. 6.6 13.3 6.6
P-Site Similarity: 6.6 20 N.A. 26.6 40 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 7 7 60 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 20 0 7 0 7 14 0 7 % D
% Glu: 7 0 7 7 0 0 0 0 27 7 0 14 0 7 7 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 54 14 0 14 0 7 14 0 20 7 60 0 7 % G
% His: 0 0 0 0 7 0 7 0 0 7 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 0 % I
% Lys: 20 0 0 7 0 0 0 14 27 0 0 7 7 0 20 % K
% Leu: 14 60 7 0 0 0 14 0 7 7 14 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 14 % M
% Asn: 0 7 7 0 0 0 0 0 0 0 0 7 0 0 7 % N
% Pro: 0 0 0 0 7 40 7 0 7 0 0 0 0 0 0 % P
% Gln: 7 7 0 47 7 0 0 0 0 0 0 14 7 7 0 % Q
% Arg: 27 20 0 7 7 7 7 0 0 0 0 7 0 54 40 % R
% Ser: 0 0 7 0 0 7 0 7 7 7 7 14 7 7 0 % S
% Thr: 7 0 14 7 60 14 7 27 0 0 7 14 0 7 0 % T
% Val: 0 0 0 0 14 7 54 20 0 7 47 7 7 0 0 % V
% Trp: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _