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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH2
All Species:
13.33
Human Site:
Y218
Identified Species:
20.95
UniProt:
Q9BQC3
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQC3
NP_001375.2
489
52083
Y218
L
E
E
Y
G
A
F
Y
V
G
G
S
K
A
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532611
487
51822
A216
R
C
L
E
E
Y
G
A
F
Y
V
G
G
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR25
489
52346
Y218
L
E
E
Y
G
A
F
Y
V
G
A
S
Q
A
S
Rat
Rattus norvegicus
Q568Y2
489
52306
Y218
L
E
E
Y
G
A
F
Y
V
G
A
S
Q
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZKI2
477
52145
E205
R
F
H
M
E
A
A
E
E
L
Q
D
C
S
M
Frog
Xenopus laevis
Q6DE00
478
52667
L208
R
F
S
P
D
L
R
L
W
P
E
S
Y
G
I
Zebra Danio
Brachydanio rerio
A4QN59
498
55134
R213
F
K
F
G
R
Q
F
R
I
K
E
G
Q
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650402
469
52077
N206
T
T
T
R
E
T
T
N
L
E
R
I
C
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09454
476
52936
N223
I
P
S
C
L
R
N
N
Q
P
T
D
L
I
F
Sea Urchin
Strong. purpuratus
XP_786110
552
60545
S224
Q
S
K
E
T
A
S
S
S
A
T
S
K
E
E
Poplar Tree
Populus trichocarpa
XP_002326199
496
54716
T208
V
A
A
C
S
R
H
T
I
G
G
L
S
W
E
Maize
Zea mays
NP_001146073
514
56668
T219
G
M
E
C
S
S
S
T
Q
K
Y
S
L
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191522
491
54825
W206
Y
R
L
G
G
L
T
W
D
L
P
E
G
S
K
Baker's Yeast
Sacchar. cerevisiae
P32461
534
59757
S231
V
G
V
F
E
K
N
S
V
L
F
G
Q
H
D
Red Bread Mold
Neurospora crassa
Q7S5C0
602
65317
G280
H
G
S
E
T
S
T
G
L
D
L
R
D
Y
S
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
88.3
N.A.
83.6
84.8
N.A.
N.A.
47.4
44.3
38.7
N.A.
29.6
N.A.
29.8
35.5
Protein Similarity:
100
N.A.
N.A.
91.6
N.A.
88.9
89.5
N.A.
N.A.
60.3
61.1
56.6
N.A.
47.6
N.A.
48.2
51.2
P-Site Identity:
100
N.A.
N.A.
0
N.A.
86.6
86.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
0
N.A.
0
20
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
93.3
93.3
N.A.
N.A.
13.3
6.6
26.6
N.A.
6.6
N.A.
6.6
26.6
Percent
Protein Identity:
27
26
N.A.
26.2
25.6
24.7
Protein Similarity:
44.1
43.3
N.A.
45.2
40.8
37.2
P-Site Identity:
13.3
20
N.A.
6.6
6.6
6.6
P-Site Similarity:
26.6
26.6
N.A.
20
26.6
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
34
7
7
0
7
14
0
0
27
0
% A
% Cys:
0
7
0
20
0
0
0
0
0
0
0
0
14
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
7
7
0
14
7
0
7
% D
% Glu:
0
20
27
20
27
0
0
7
7
7
14
7
0
7
20
% E
% Phe:
7
14
7
7
0
0
27
0
7
0
7
0
0
0
14
% F
% Gly:
7
14
0
14
27
0
7
7
0
27
14
20
14
7
7
% G
% His:
7
0
7
0
0
0
7
0
0
0
0
0
0
7
0
% H
% Ile:
7
0
0
0
0
0
0
0
14
0
0
7
0
14
7
% I
% Lys:
0
7
7
0
0
7
0
0
0
14
0
0
14
0
7
% K
% Leu:
20
0
14
0
7
14
0
7
14
20
7
7
14
0
0
% L
% Met:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
14
14
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
7
0
0
0
0
0
14
7
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
0
14
0
7
0
27
0
0
% Q
% Arg:
20
7
0
7
7
14
7
7
0
0
7
7
0
0
0
% R
% Ser:
0
7
20
0
14
14
14
14
7
0
0
40
7
20
27
% S
% Thr:
7
7
7
0
14
7
20
14
0
0
14
0
0
7
0
% T
% Val:
14
0
7
0
0
0
0
0
27
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
0
% W
% Tyr:
7
0
0
20
0
7
0
20
0
7
7
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _