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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SELS All Species: 21.52
Human Site: S146 Identified Species: 52.59
UniProt: Q9BQE4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQE4 NP_060915.2 189 21163 S146 D S P G P S T S S V L K R K S
Chimpanzee Pan troglodytes NP_001108228 189 20966 S146 D S P G P S T S S V L K R K S
Rhesus Macaque Macaca mulatta NP_001108227 190 21127 S147 S P G P S T S S V V V K R K S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9BCZ4 190 21341 S147 G P G P S T S S V I P K G K S
Rat Rattus norvegicus Q8VHV8 190 21217 S147 G P G P S T S S V I P K G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507741 204 22874 T162 E T D P G P S T S S V I P K P
Chicken Gallus gallus NP_001019905 194 20994 S151 E S G A S T S S A V P K S K P
Frog Xenopus laevis Q6AZH0 193 21223 S150 S S S P S T S S S A P K P K P
Zebra Danio Brachydanio rerio Q0VFV6 190 21033 S147 N T E E A A S S S S L R P K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001177364 186 21406 Q143 K A A K E A E Q A E A R G V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 94.7 N.A. N.A. 83.1 82.6 N.A. 60.7 63.4 53.8 48.9 N.A. N.A. N.A. N.A. 34.3
Protein Similarity: 100 99.4 97.8 N.A. N.A. 91 91 N.A. 75.4 75.7 65.8 69.4 N.A. N.A. N.A. N.A. 55.5
P-Site Identity: 100 100 40 N.A. N.A. 26.6 26.6 N.A. 13.3 33.3 33.3 26.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 60 N.A. N.A. 46.6 46.6 N.A. 46.6 60 46.6 66.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 10 20 0 0 20 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 0 10 10 10 0 10 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 40 20 10 0 0 0 0 0 0 0 30 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 20 0 10 0 0 0 % I
% Lys: 10 0 0 10 0 0 0 0 0 0 0 70 0 90 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 30 20 50 20 10 0 0 0 0 40 0 30 0 30 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 20 30 0 0 % R
% Ser: 20 40 10 0 50 20 70 80 50 20 0 0 10 0 50 % S
% Thr: 0 20 0 0 0 50 20 10 0 0 0 0 0 0 20 % T
% Val: 0 0 0 0 0 0 0 0 30 40 20 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _