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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT12 All Species: 39.09
Human Site: S309 Identified Species: 78.18
UniProt: Q9BQG2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQG2 NP_113626.1 462 52076 S309 C L K E D C P S L N G V H N T
Chimpanzee Pan troglodytes XP_517859 574 64187 S421 C L K E D C P S L N G V H N T
Rhesus Macaque Macaca mulatta XP_001099246 462 52072 S309 C L K E D C P S L N G V H N T
Dog Lupus familis XP_545998 460 51870 S307 C L K E D C P S L H G V H N T
Cat Felis silvestris
Mouse Mus musculus Q9DCN1 462 51492 S309 C V R E T C P S L Q G V H N T
Rat Rattus norvegicus NP_001102480 462 51343 S309 C V R E N C P S L H G V H N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505905 676 73615 S523 C L K E D C P S L I G V H N T
Chicken Gallus gallus XP_001231287 465 52165 S312 C V K E D C P S L Q G V H N T
Frog Xenopus laevis NP_001088355 458 51377 S305 C L K N E C P S L R G I H N T
Zebra Danio Brachydanio rerio NP_001017675 433 48091 S280 C L R A G C R S L Q G V Y N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19427 374 42070 G236 V R H R G S A G G V F T A V A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53164 384 43498 Y246 L A R S K K R Y G D F V L Y S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 98 91.3 N.A. 87.8 87.6 N.A. 56.2 74.6 64.5 51.2 N.A. N.A. N.A. 26.6 N.A.
Protein Similarity: 100 75.9 99.3 96.7 N.A. 95 94.3 N.A. 62.1 86.4 80.3 68.4 N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 73.3 73.3 N.A. 93.3 86.6 73.3 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. 93.3 93.3 86.6 73.3 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 9 0 0 0 0 0 9 0 9 % A
% Cys: 84 0 0 0 0 84 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 67 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % F
% Gly: 0 0 0 0 17 0 0 9 17 0 84 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 17 0 0 75 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 0 59 0 9 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 59 0 0 0 0 0 0 84 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 25 0 0 0 84 0 % N
% Pro: 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 % Q
% Arg: 0 9 34 9 0 0 17 0 0 9 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 9 0 84 0 0 0 0 0 0 9 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 84 % T
% Val: 9 25 0 0 0 0 0 0 0 9 0 84 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _