KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIF1L
All Species:
20
Human Site:
S134
Identified Species:
44
UniProt:
Q9BQI0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BQI0
NP_113614.1
150
17068
S134
E
G
K
A
N
E
S
S
P
K
P
V
G
P
P
Chimpanzee
Pan troglodytes
XP_001154743
147
16784
K131
Y
E
E
K
A
R
E
K
E
K
P
T
G
P
P
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
K131
Y
E
E
K
A
R
E
K
E
K
P
T
G
P
P
Dog
Lupus familis
XP_850690
246
26736
S230
E
G
K
A
N
E
S
S
P
K
P
V
G
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQX4
150
17005
S134
E
G
K
A
N
E
S
S
P
K
P
A
G
P
P
Rat
Rattus norvegicus
P55009
147
16809
H131
Y
E
E
K
N
K
E
H
Q
K
P
T
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521721
160
17870
S144
E
G
K
A
N
E
S
S
P
R
P
S
G
P
P
Chicken
Gallus gallus
XP_415461
145
16272
N129
E
G
K
A
N
E
S
N
P
K
P
S
G
P
P
Frog
Xenopus laevis
NP_001085758
148
16998
S132
E
G
K
N
E
V
T
S
P
K
P
M
G
P
P
Zebra Danio
Brachydanio rerio
NP_942571
148
16914
S132
E
D
K
A
N
G
S
S
C
K
P
D
G
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
E200
E
E
R
R
R
E
E
E
E
R
A
Q
R
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.3
63.3
55.2
N.A.
96
62
N.A.
71.2
76.6
64
76
N.A.
22.1
N.A.
N.A.
N.A.
Protein Similarity:
100
78.6
78.6
57.7
N.A.
96.6
76.6
N.A.
77.5
86.6
82.6
85.3
N.A.
37.3
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
33.3
100
N.A.
93.3
40
N.A.
86.6
86.6
66.6
73.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
40
100
N.A.
93.3
53.3
N.A.
93.3
93.3
80
73.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
55
19
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
73
37
28
0
10
55
37
10
28
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
55
0
0
0
10
0
0
0
0
0
0
91
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
64
28
0
10
0
19
0
82
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
64
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
55
0
91
0
0
91
91
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% Q
% Arg:
0
0
10
10
10
19
0
0
0
19
0
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
55
55
0
0
0
19
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
28
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _