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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A21 All Species: 22.73
Human Site: S52 Identified Species: 38.46
UniProt: Q9BQT8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQT8 NP_085134.1 299 33303 S52 R C A T D P N S Y K S L V D S
Chimpanzee Pan troglodytes XP_522830 299 33181 S52 R C A T D P N S Y K S L V D S
Rhesus Macaque Macaca mulatta XP_001090467 299 33159 S52 R C A T D P N S Y K S L V D S
Dog Lupus familis XP_547777 364 39873 S117 R C A T D P N S Y K S L G D S
Cat Felis silvestris
Mouse Mus musculus Q8BZ09 298 33210 S51 R S V T D P Q S Y R T V R G S
Rat Rattus norvegicus Q99JD3 298 33260 S51 R S V T D P Q S Y K S L R D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511236 245 27301 I26 Y K G I L P P I L A E T P K R
Chicken Gallus gallus XP_421247 301 33080 S51 R G K T D P T S Y K S L G D C
Frog Xenopus laevis Q6GQ22 291 32540 W60 M H A I V R I W R E E G V K A
Zebra Danio Brachydanio rerio Q6DHC3 353 39081 H84 V W Y K A P G H F S G T L D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34519 312 34200 F64 E R S A T P K F R G P I D C V
Sea Urchin Strong. purpuratus XP_783093 294 32620 C53 K Y N G M W D C V R Q M T K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99297 307 33988 R58 A V G K Q V E R Y N G V I D C
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 V67 E I I G G G P V Y K G T L P T
Conservation
Percent
Protein Identity: 100 99.3 97.9 70.3 N.A. 81.2 82.2 N.A. 70.9 81.7 27.7 26.6 N.A. N.A. N.A. 27.5 63.5
Protein Similarity: 100 99.3 99 75 N.A. 88.9 87.9 N.A. 75.2 88.3 46.1 44.1 N.A. N.A. N.A. 46.4 78.9
P-Site Identity: 100 100 100 93.3 N.A. 46.6 73.3 N.A. 6.6 66.6 13.3 13.3 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 66.6 73.3 N.A. 6.6 66.6 26.6 33.3 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 56.6 41.4
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 36 8 8 0 0 0 0 8 0 0 0 0 15 % A
% Cys: 0 29 0 0 0 0 0 8 0 0 0 0 0 8 15 % C
% Asp: 0 0 0 0 50 0 8 0 0 0 0 0 8 58 0 % D
% Glu: 15 0 0 0 0 0 8 0 0 8 15 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % F
% Gly: 0 8 15 15 8 8 8 0 0 8 22 8 15 8 0 % G
% His: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 15 0 0 8 8 0 0 0 8 8 0 0 % I
% Lys: 8 8 8 15 0 0 8 0 0 50 0 0 0 22 8 % K
% Leu: 0 0 0 0 8 0 0 0 8 0 0 43 15 0 0 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 29 0 0 8 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 72 15 0 0 0 8 0 8 8 0 % P
% Gln: 0 0 0 0 8 0 15 0 0 0 8 0 0 0 0 % Q
% Arg: 50 8 0 0 0 8 0 8 15 15 0 0 15 0 8 % R
% Ser: 0 15 8 0 0 0 0 50 0 8 43 0 0 0 43 % S
% Thr: 0 0 0 50 8 0 8 0 0 0 8 22 8 0 8 % T
% Val: 8 8 15 0 8 8 0 8 8 0 0 15 29 0 8 % V
% Trp: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 8 8 0 0 0 0 0 65 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _