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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A21 All Species: 34.85
Human Site: T253 Identified Species: 58.97
UniProt: Q9BQT8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BQT8 NP_085134.1 299 33303 T253 K Y R T C F K T M A T V Y Q E
Chimpanzee Pan troglodytes XP_522830 299 33181 T253 K Y R T C F K T M A T V Y Q E
Rhesus Macaque Macaca mulatta XP_001090467 299 33159 T253 K Y R T C F K T M A T V Y Q E
Dog Lupus familis XP_547777 364 39873 T318 K Y R T C F K T M A T V Y Q E
Cat Felis silvestris
Mouse Mus musculus Q8BZ09 298 33210 T252 K Y R S C F K T M E M I Y R E
Rat Rattus norvegicus Q99JD3 298 33260 T252 K Y R G C F K T M E T V Y R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511236 245 27301 Q205 Q T M A T V Y Q E E G F F A L
Chicken Gallus gallus XP_421247 301 33080 T252 K Y R T C L K T M A T V Y K E
Frog Xenopus laevis Q6GQ22 291 32540 C248 S Y K G T L D C L L Q T W K N
Zebra Danio Brachydanio rerio Q6DHC3 353 39081 S282 K L S T Q V S S S T C S V M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34519 312 34200 C262 K Y K N T L D C A M Q I W K K
Sea Urchin Strong. purpuratus XP_783093 294 32620 T248 K Y K G C F R T I S M V Y R E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99297 307 33988 S258 K Y N W C L P S L L V I Y R E
Red Bread Mold Neurospora crassa Q7S2H8 333 36079 Y270 V H K N I P V Y D G G M V K T
Conservation
Percent
Protein Identity: 100 99.3 97.9 70.3 N.A. 81.2 82.2 N.A. 70.9 81.7 27.7 26.6 N.A. N.A. N.A. 27.5 63.5
Protein Similarity: 100 99.3 99 75 N.A. 88.9 87.9 N.A. 75.2 88.3 46.1 44.1 N.A. N.A. N.A. 46.4 78.9
P-Site Identity: 100 100 100 100 N.A. 66.6 80 N.A. 0 86.6 6.6 13.3 N.A. N.A. N.A. 13.3 53.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 13.3 93.3 33.3 26.6 N.A. N.A. N.A. 46.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 56.6 41.4
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 0
P-Site Similarity: N.A. N.A. N.A. N.A. 60 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 8 36 0 0 0 8 0 % A
% Cys: 0 0 0 0 65 0 0 15 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 15 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 8 22 0 0 0 0 65 % E
% Phe: 0 0 0 0 0 50 0 0 0 0 0 8 8 0 0 % F
% Gly: 0 0 0 22 0 0 0 0 0 8 15 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 22 0 0 0 % I
% Lys: 79 0 29 0 0 0 50 0 0 0 0 0 0 29 15 % K
% Leu: 0 8 0 0 0 29 0 0 15 15 0 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 50 8 15 8 0 8 0 % M
% Asn: 0 0 8 15 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 8 0 0 15 0 0 29 0 % Q
% Arg: 0 0 50 0 0 0 8 0 0 0 0 0 0 29 0 % R
% Ser: 8 0 8 8 0 0 8 15 8 8 0 8 0 0 0 % S
% Thr: 0 8 0 43 22 0 0 58 0 8 43 8 0 0 8 % T
% Val: 8 0 0 0 0 15 8 0 0 0 8 50 15 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 15 0 0 % W
% Tyr: 0 79 0 0 0 0 8 8 0 0 0 0 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _