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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD4 All Species: 21.21
Human Site: S622 Identified Species: 35.9
UniProt: Q9BRC7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRC7 NP_116115.1 762 87585 S622 F H P E K P I S P F K A Q T L
Chimpanzee Pan troglodytes XP_526029 762 87514 S622 F H P E K P I S P F K A Q T L
Rhesus Macaque Macaca mulatta XP_001091488 799 91444 S659 F H P E R P I S P F K A Q T L
Dog Lupus familis XP_536069 769 88595 S629 F H P E R P V S P F R A Q T L
Cat Felis silvestris
Mouse Mus musculus Q8K3R3 807 92676 S667 F N P E R P I S L Y K A Q I L
Rat Rattus norvegicus Q62711 772 88948 S632 F N P M K P V S L Y K A Q I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 M602 F D P R D P S M E G P W W A P
Chicken Gallus gallus Q2VRL0 637 72514 G505 T F N P H N V G R Y S N P L S
Frog Xenopus laevis Q32NH8 758 87399 E617 P D Q P Q G T E G Y S P V N L
Zebra Danio Brachydanio rerio A5D6R3 784 89362 P636 P E N T G G G P G H I P T Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 P679 F D P F A D A P V D G V I A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 K620 N M Q F N P L K P G D Q Y T Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LY51 584 66443 P452 F D P E A T L P V K T T L R V
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 P711 L K P K K L L P V V T K A K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 92.9 84.4 N.A. 71.8 72.6 N.A. 46.7 37.7 59.9 45 N.A. 25.1 N.A. N.A. 41.3
Protein Similarity: 100 99.7 94.4 91 N.A. 81.4 84.4 N.A. 62.5 54.4 77.9 65.4 N.A. 39.6 N.A. N.A. 58.7
P-Site Identity: 100 100 93.3 80 N.A. 66.6 60 N.A. 20 0 6.6 6.6 N.A. 13.3 N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 86.6 80 N.A. 20 13.3 20 6.6 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.3 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 8 0 0 0 0 43 8 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 29 0 0 8 8 0 0 0 8 8 0 0 0 0 % D
% Glu: 0 8 0 43 0 0 0 8 8 0 0 0 0 0 0 % E
% Phe: 65 8 0 15 0 0 0 0 0 29 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 15 8 8 15 15 8 0 0 0 0 % G
% His: 0 29 0 0 8 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 29 0 0 0 8 0 8 15 0 % I
% Lys: 0 8 0 8 29 0 0 8 0 8 36 8 0 8 0 % K
% Leu: 8 0 0 0 0 8 22 0 15 0 0 0 8 8 58 % L
% Met: 0 8 0 8 0 0 0 8 0 0 0 0 0 0 8 % M
% Asn: 8 15 15 0 8 8 0 0 0 0 0 8 0 8 0 % N
% Pro: 15 0 72 15 0 58 0 29 36 0 8 15 8 0 8 % P
% Gln: 0 0 15 0 8 0 0 0 0 0 0 8 43 8 8 % Q
% Arg: 0 0 0 8 22 0 0 0 8 0 8 0 0 8 0 % R
% Ser: 0 0 0 0 0 0 8 43 0 0 15 0 0 0 8 % S
% Thr: 8 0 0 8 0 8 8 0 0 0 15 8 8 36 0 % T
% Val: 0 0 0 0 0 0 22 0 22 8 0 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 29 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _