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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
28.79
Human Site:
S635
Identified Species:
48.72
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
S635
T
L
L
I
Q
V
I
S
G
Q
Q
L
P
K
V
Chimpanzee
Pan troglodytes
XP_526029
762
87514
S635
T
L
L
I
Q
V
I
S
G
Q
Q
L
P
K
V
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
S672
T
L
L
I
Q
V
I
S
G
Q
Q
L
P
K
L
Dog
Lupus familis
XP_536069
769
88595
S642
T
L
L
I
Q
V
I
S
G
Q
Q
L
P
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
S680
I
L
V
V
Q
V
I
S
G
Q
Q
L
P
K
V
Rat
Rattus norvegicus
Q62711
772
88948
S645
I
L
V
V
Q
V
I
S
G
Q
R
L
P
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
L615
A
P
K
K
L
S
I
L
V
I
S
G
Q
Q
L
Chicken
Gallus gallus
Q2VRL0
637
72514
I518
L
S
L
S
I
R
L
I
S
G
H
Q
L
P
P
Frog
Xenopus laevis
Q32NH8
758
87399
S630
N
L
S
I
L
V
I
S
A
Q
Q
L
P
K
V
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
S649
Q
L
T
I
R
V
I
S
A
Q
Q
L
P
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
V692
A
A
Q
C
S
V
K
V
I
A
G
Q
F
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
V633
T
Q
H
V
T
L
T
V
I
S
G
Q
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
E465
R
V
T
I
Y
M
G
E
G
W
Y
Y
D
F
P
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
E724
K
M
I
P
L
I
Y
E
H
F
E
N
G
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
93.3
93.3
N.A.
80
73.3
N.A.
6.6
6.6
73.3
66.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
13.3
73.3
80
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
0
0
15
8
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
0
0
0
15
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% F
% Gly:
0
0
0
0
0
0
8
0
50
8
15
8
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
15
0
8
50
8
8
65
8
15
8
0
0
0
0
8
% I
% Lys:
8
0
8
8
0
0
8
0
0
0
0
0
0
58
0
% K
% Leu:
8
58
36
0
22
8
8
8
0
0
0
58
8
15
15
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
58
8
22
% P
% Gln:
8
8
8
0
43
0
0
0
0
58
50
22
15
8
0
% Q
% Arg:
8
0
0
0
8
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
8
8
8
8
0
58
8
8
8
0
0
8
8
% S
% Thr:
36
0
15
0
8
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
8
15
22
0
65
0
15
8
0
0
0
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _