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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD4 All Species: 18.48
Human Site: T400 Identified Species: 31.28
UniProt: Q9BRC7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRC7 NP_116115.1 762 87585 T400 Q T M A R H L T E I L G E Q L
Chimpanzee Pan troglodytes XP_526029 762 87514 T400 Q T M A R H L T E I L G E Q L
Rhesus Macaque Macaca mulatta XP_001091488 799 91444 T400 Q T M A R H L T E I L G E Q L
Dog Lupus familis XP_536069 769 88595 T402 Q V M A C H L T E I L G E Q L
Cat Felis silvestris
Mouse Mus musculus Q8K3R3 807 92676 T400 R T M A H H L T E I L G E Q L
Rat Rattus norvegicus Q62711 772 88948 I400 K T M A H H L I A I L G E Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 E387 R V L A R H M E R I L G D L L
Chicken Gallus gallus Q2VRL0 637 72514 V299 A L K F K I L V K N K K C G T
Frog Xenopus laevis Q32NH8 758 87399 K400 D A M A Q H L K S I L G N K L
Zebra Danio Brachydanio rerio A5D6R3 784 89362 Q423 A I M A Q Q L Q S I L G K K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 D431 Y K L A K Y C D D F F G D L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 V409 K V M A Q I C V S I L K D K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LY51 584 66443 S246 L K K R I M I S T K P P K E Y
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 R488 K L A S L I M R E V L A E Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 92.9 84.4 N.A. 71.8 72.6 N.A. 46.7 37.7 59.9 45 N.A. 25.1 N.A. N.A. 41.3
Protein Similarity: 100 99.7 94.4 91 N.A. 81.4 84.4 N.A. 62.5 54.4 77.9 65.4 N.A. 39.6 N.A. N.A. 58.7
P-Site Identity: 100 100 100 86.6 N.A. 86.6 73.3 N.A. 46.6 6.6 53.3 46.6 N.A. 20 N.A. N.A. 33.3
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 80 N.A. 73.3 20 66.6 66.6 N.A. 53.3 N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 23.3 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 43.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 79 0 0 0 0 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 8 0 15 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 8 0 0 0 22 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 43 0 0 0 50 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 72 0 8 0 % G
% His: 0 0 0 0 15 58 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 22 8 8 0 72 0 0 0 0 0 % I
% Lys: 22 15 15 0 15 0 0 8 8 8 8 15 15 22 0 % K
% Leu: 8 15 15 0 8 0 65 0 0 0 79 0 0 15 86 % L
% Met: 0 0 65 0 0 8 15 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % P
% Gln: 29 0 0 0 22 8 0 8 0 0 0 0 0 50 0 % Q
% Arg: 15 0 0 8 29 0 0 8 8 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 8 22 0 0 0 0 0 0 % S
% Thr: 0 36 0 0 0 0 0 36 8 0 0 0 0 0 8 % T
% Val: 0 22 0 0 0 0 0 15 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _