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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD4
All Species:
34.85
Human Site:
Y272
Identified Species:
58.97
UniProt:
Q9BRC7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRC7
NP_116115.1
762
87585
Y272
S
M
D
G
F
L
S
Y
L
C
S
K
D
G
D
Chimpanzee
Pan troglodytes
XP_526029
762
87514
Y272
S
M
D
G
F
L
S
Y
L
C
S
K
D
G
D
Rhesus Macaque
Macaca mulatta
XP_001091488
799
91444
Y272
S
M
D
G
F
L
S
Y
L
C
S
K
D
G
D
Dog
Lupus familis
XP_536069
769
88595
Y274
S
M
D
G
F
L
S
Y
L
C
S
K
D
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3R3
807
92676
Y272
S
K
D
G
F
L
K
Y
L
C
S
K
D
G
N
Rat
Rattus norvegicus
Q62711
772
88948
Y272
S
K
D
G
F
L
S
Y
L
C
S
A
D
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
Y259
T
K
D
G
F
L
M
Y
L
L
S
A
D
G
N
Chicken
Gallus gallus
Q2VRL0
637
72514
L176
S
S
S
H
N
T
Y
L
V
S
D
Q
L
I
G
Frog
Xenopus laevis
Q32NH8
758
87399
Y272
S
I
D
G
F
L
V
Y
L
C
S
P
E
G
S
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y295
T
Q
N
G
F
T
M
Y
M
L
S
K
E
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
Y301
S
L
D
G
F
K
R
Y
L
M
S
D
E
N
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
F281
T
M
D
G
F
F
L
F
M
M
G
P
S
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LY51
584
66443
T123
T
G
H
N
S
Y
L
T
G
N
Q
L
S
S
D
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
D362
T
Q
L
T
M
G
Q
D
G
F
T
K
F
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
92.9
84.4
N.A.
71.8
72.6
N.A.
46.7
37.7
59.9
45
N.A.
25.1
N.A.
N.A.
41.3
Protein Similarity:
100
99.7
94.4
91
N.A.
81.4
84.4
N.A.
62.5
54.4
77.9
65.4
N.A.
39.6
N.A.
N.A.
58.7
P-Site Identity:
100
100
100
100
N.A.
80
80
N.A.
60
6.6
66.6
40
N.A.
46.6
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
73.3
20
80
66.6
N.A.
60
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% C
% Asp:
0
0
72
0
0
0
0
8
0
0
8
8
50
0
43
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% E
% Phe:
0
0
0
0
79
8
0
8
0
8
0
0
8
0
0
% F
% Gly:
0
8
0
79
0
8
0
0
15
0
8
0
0
65
8
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
22
0
0
0
8
8
0
0
0
0
50
0
0
8
% K
% Leu:
0
8
8
0
0
58
15
8
65
15
0
8
8
8
8
% L
% Met:
0
36
0
0
8
0
15
0
15
15
0
0
0
0
0
% M
% Asn:
0
0
8
8
8
0
0
0
0
8
0
0
0
15
22
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% P
% Gln:
0
15
0
0
0
0
8
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
65
8
8
0
8
0
36
0
0
8
72
0
15
8
8
% S
% Thr:
36
0
0
8
0
15
0
8
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _