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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS25
All Species:
39.7
Human Site:
Y112
Identified Species:
72.78
UniProt:
Q9BRG1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRG1
NP_115729.1
176
20748
Y112
E
E
W
G
K
L
I
Y
Q
W
V
S
R
S
G
Chimpanzee
Pan troglodytes
XP_530480
176
20743
Y112
E
E
W
G
K
L
I
Y
Q
W
V
S
R
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849270
202
23665
Y138
E
E
W
G
K
L
I
Y
Q
W
V
S
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ80
176
20729
Y112
E
E
W
G
K
L
I
Y
Q
W
V
S
R
S
G
Rat
Rattus norvegicus
P0C0A1
176
20743
Y112
E
E
W
G
K
L
I
Y
Q
W
V
S
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6AX45
174
20714
Y110
D
E
W
G
K
V
I
Y
Q
W
V
S
K
N
G
Zebra Danio
Brachydanio rerio
Q6NWF4
174
20687
Y110
E
E
W
G
K
L
I
Y
Q
W
V
S
K
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610398
174
20590
Y110
E
E
Y
G
N
M
V
Y
D
W
V
Q
E
T
G
Honey Bee
Apis mellifera
XP_395839
175
20447
Y111
E
E
W
G
E
I
I
Y
N
W
A
Q
E
N
G
Nematode Worm
Caenorhab. elegans
NP_493230
183
21455
Y118
D
V
W
A
N
M
I
Y
Q
W
A
V
E
N
A
Sea Urchin
Strong. purpuratus
XP_787383
175
20595
Y111
E
E
W
G
N
L
I
Y
K
W
A
G
N
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZC9
179
20663
L112
Q
D
W
A
D
I
V
L
Q
F
V
R
D
N
G
Baker's Yeast
Sacchar. cerevisiae
P47142
202
23539
L136
D
S
W
A
S
L
I
L
Q
W
F
E
D
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
86.1
N.A.
98.8
98.3
N.A.
N.A.
N.A.
76.6
76.6
N.A.
43.1
55.6
42
56.8
Protein Similarity:
100
100
N.A.
87.1
N.A.
100
100
N.A.
N.A.
N.A.
89.1
87.5
N.A.
65.9
69.8
63.9
73.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
73.3
86.6
N.A.
46.6
53.3
33.3
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
100
100
N.A.
73.3
73.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.1
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
0
0
0
0
0
24
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
8
0
0
8
0
0
0
8
0
0
0
16
0
0
% D
% Glu:
70
77
0
0
8
0
0
0
0
0
0
8
24
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
0
77
0
0
0
0
0
0
0
8
0
0
93
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
16
85
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
54
0
0
0
8
0
0
0
16
0
0
% K
% Leu:
0
0
0
0
0
62
0
16
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
24
0
0
0
8
0
0
0
8
39
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
77
0
0
16
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
39
0
0
% R
% Ser:
0
8
0
0
8
0
0
0
0
0
0
54
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
8
16
0
0
0
70
8
0
0
0
% V
% Trp:
0
0
93
0
0
0
0
0
0
93
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _