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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL45 All Species: 9.7
Human Site: S121 Identified Species: 19.39
UniProt: Q9BRJ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRJ2 NP_115727 306 35351 S121 K T M A S Q V S I R R I K D Y
Chimpanzee Pan troglodytes XP_512553 306 35239 S121 K T M A S Q V S I R R I K D Y
Rhesus Macaque Macaca mulatta XP_001082116 97 11053
Dog Lupus familis XP_850801 303 35026 S121 K K V A S Q L S I R K I R E H
Cat Felis silvestris
Mouse Mus musculus Q9D0Q7 306 35392 A121 K N A A S Q L A I R K I R E F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423896 280 32268 T114 R M E K L K Q T A A S Q L A L
Frog Xenopus laevis P59480 309 35333 A121 Q T A A S Q L A I R K V K E Y
Zebra Danio Brachydanio rerio NP_956601 251 29305 Q84 E F P G I G Q Q I F I D A H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCX3 361 41593 A152 K K S K S L M A V R K I R S Y
Honey Bee Apis mellifera XP_625034 332 38858 A138 K K S K S F I A L R K I K G Y
Nematode Worm Caenorhab. elegans Q95Y71 357 41297 G158 K F Y N W R M G T N R I R K K
Sea Urchin Strong. purpuratus XP_793386 338 39556 A144 N V G V T Q M A Q R K I R Q F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 26.7 81 N.A. 79.4 N.A. N.A. N.A. 51.9 54 41.5 N.A. 35.7 33.4 31.9 39.9
Protein Similarity: 100 99.3 28.7 91.1 N.A. 89.5 N.A. N.A. N.A. 68.3 72.4 57.8 N.A. 54 51.8 48.1 60.3
P-Site Identity: 100 100 0 53.3 N.A. 46.6 N.A. N.A. N.A. 0 53.3 6.6 N.A. 33.3 40 20 20
P-Site Similarity: 100 100 0 93.3 N.A. 86.6 N.A. N.A. N.A. 20 93.3 13.3 N.A. 66.6 66.6 40 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 42 0 0 0 42 9 9 0 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % D
% Glu: 9 0 9 0 0 0 0 0 0 0 0 0 0 25 0 % E
% Phe: 0 17 0 0 0 9 0 0 0 9 0 0 0 0 17 % F
% Gly: 0 0 9 9 0 9 0 9 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % H
% Ile: 0 0 0 0 9 0 9 0 50 0 9 67 0 0 0 % I
% Lys: 59 25 0 25 0 9 0 0 0 0 50 0 34 9 9 % K
% Leu: 0 0 0 0 9 9 25 0 9 0 0 0 9 0 9 % L
% Met: 0 9 17 0 0 0 25 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 9 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 50 17 9 9 0 0 9 0 9 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 67 25 0 42 0 0 % R
% Ser: 0 0 17 0 59 0 0 25 0 0 9 0 0 9 0 % S
% Thr: 0 25 0 0 9 0 0 9 9 0 0 0 0 0 0 % T
% Val: 0 9 9 9 0 0 17 0 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _