KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL45
All Species:
30.61
Human Site:
T218
Identified Species:
61.21
UniProt:
Q9BRJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRJ2
NP_115727
306
35351
T218
Q
I
T
V
R
M
H
T
R
Q
T
L
A
I
Y
Chimpanzee
Pan troglodytes
XP_512553
306
35239
T218
Q
I
T
V
R
M
H
T
R
Q
T
L
A
I
Y
Rhesus Macaque
Macaca mulatta
XP_001082116
97
11053
L16
L
S
R
L
S
R
V
L
G
W
W
S
R
Q
P
Dog
Lupus familis
XP_850801
303
35026
T218
Q
V
T
V
R
M
H
T
R
Q
T
L
A
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Q7
306
35392
T218
Q
V
T
V
R
L
H
T
R
Q
T
L
A
I
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423896
280
32268
T199
R
V
A
H
V
R
C
T
S
V
V
N
Q
G
N
Frog
Xenopus laevis
P59480
309
35333
N218
Q
V
T
V
R
M
H
N
K
Q
T
L
I
V
Y
Zebra Danio
Brachydanio rerio
NP_956601
251
29305
F169
T
L
A
I
Y
D
R
F
G
R
L
M
L
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCX3
361
41593
S249
Q
V
T
V
R
F
H
S
Q
Q
M
L
A
I
Y
Honey Bee
Apis mellifera
XP_625034
332
38858
T235
Q
V
T
I
R
F
H
T
Q
Q
I
L
C
I
Y
Nematode Worm
Caenorhab. elegans
Q95Y71
357
41297
T258
Q
I
T
V
R
M
H
T
R
Q
K
L
A
V
Y
Sea Urchin
Strong. purpuratus
XP_793386
338
39556
T241
Q
V
T
V
R
F
H
T
R
Q
T
L
A
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.7
81
N.A.
79.4
N.A.
N.A.
N.A.
51.9
54
41.5
N.A.
35.7
33.4
31.9
39.9
Protein Similarity:
100
99.3
28.7
91.1
N.A.
89.5
N.A.
N.A.
N.A.
68.3
72.4
57.8
N.A.
54
51.8
48.1
60.3
P-Site Identity:
100
100
0
93.3
N.A.
86.6
N.A.
N.A.
N.A.
6.6
66.6
0
N.A.
66.6
60
86.6
86.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
N.A.
N.A.
N.A.
20
86.6
26.6
N.A.
86.6
80
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
0
0
0
0
59
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
25
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
17
0
0
0
0
17
0
% G
% His:
0
0
0
9
0
0
75
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
17
0
0
0
0
0
0
9
0
9
59
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% K
% Leu:
9
9
0
9
0
9
0
9
0
0
9
75
9
0
0
% L
% Met:
0
0
0
0
0
42
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
75
0
0
0
0
0
0
0
17
75
0
0
9
9
0
% Q
% Arg:
9
0
9
0
75
17
9
0
50
9
0
0
9
0
0
% R
% Ser:
0
9
0
0
9
0
0
9
9
0
0
9
0
0
0
% S
% Thr:
9
0
75
0
0
0
0
67
0
0
50
0
0
0
0
% T
% Val:
0
59
0
67
9
0
9
0
0
9
9
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _