Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL45 All Species: 21.82
Human Site: T221 Identified Species: 43.64
UniProt: Q9BRJ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRJ2 NP_115727 306 35351 T221 V R M H T R Q T L A I Y D R F
Chimpanzee Pan troglodytes XP_512553 306 35239 T221 V R M H T R Q T L A I Y D R F
Rhesus Macaque Macaca mulatta XP_001082116 97 11053 W19 L S R V L G W W S R Q P V L V
Dog Lupus familis XP_850801 303 35026 T221 V R M H T R Q T L A I Y D R F
Cat Felis silvestris
Mouse Mus musculus Q9D0Q7 306 35392 T221 V R L H T R Q T L A I Y D R F
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423896 280 32268 V202 H V R C T S V V N Q G N L Y G
Frog Xenopus laevis P59480 309 35333 T221 V R M H N K Q T L I V Y D R F
Zebra Danio Brachydanio rerio NP_956601 251 29305 L172 I Y D R F G R L M L G D E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCX3 361 41593 M252 V R F H S Q Q M L A I Y D R F
Honey Bee Apis mellifera XP_625034 332 38858 I238 I R F H T Q Q I L C I Y D R F
Nematode Worm Caenorhab. elegans Q95Y71 357 41297 K261 V R M H T R Q K L A V Y D R F
Sea Urchin Strong. purpuratus XP_793386 338 39556 T244 V R F H T R Q T L A I Y D R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 26.7 81 N.A. 79.4 N.A. N.A. N.A. 51.9 54 41.5 N.A. 35.7 33.4 31.9 39.9
Protein Similarity: 100 99.3 28.7 91.1 N.A. 89.5 N.A. N.A. N.A. 68.3 72.4 57.8 N.A. 54 51.8 48.1 60.3
P-Site Identity: 100 100 0 100 N.A. 93.3 N.A. N.A. N.A. 6.6 73.3 0 N.A. 73.3 66.6 86.6 93.3
P-Site Similarity: 100 100 6.6 100 N.A. 100 N.A. N.A. N.A. 6.6 86.6 26.6 N.A. 86.6 80 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 9 75 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 9 % E
% Phe: 0 0 25 0 9 0 0 0 0 0 0 0 0 0 75 % F
% Gly: 0 0 0 0 0 17 0 0 0 0 17 0 0 0 9 % G
% His: 9 0 0 75 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 0 0 9 0 9 59 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % K
% Leu: 9 0 9 0 9 0 0 9 75 9 0 0 9 9 0 % L
% Met: 0 0 42 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 0 0 0 17 75 0 0 9 9 0 0 0 0 % Q
% Arg: 0 75 17 9 0 50 9 0 0 9 0 0 0 75 0 % R
% Ser: 0 9 0 0 9 9 0 0 9 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 67 0 0 50 0 0 0 0 0 0 0 % T
% Val: 67 9 0 9 0 0 9 9 0 0 17 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 75 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _