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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRPL45 All Species: 26.97
Human Site: T279 Identified Species: 53.94
UniProt: Q9BRJ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRJ2 NP_115727 306 35351 T279 P K Q P I L K T V M I P G P Q
Chimpanzee Pan troglodytes XP_512553 306 35239 T279 P K Q P I L K T V M I P G P Q
Rhesus Macaque Macaca mulatta XP_001082116 97 11053 I76 P E K L D H P I H L A C T A G
Dog Lupus familis XP_850801 303 35026 T279 H K Q P I L K T V M I P G P Q
Cat Felis silvestris
Mouse Mus musculus Q9D0Q7 306 35392 T279 P K Q P I L K T L M I P G P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423896 280 32268 R259 V N P Y G T W R M H G K I V P
Frog Xenopus laevis P59480 309 35333 T278 P K E P I V K T V L L P G Q Q
Zebra Danio Brachydanio rerio NP_956601 251 29305 S230 I P G P K L K S G E Q F E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VCX3 361 41593 L324 A E E P P K E L S A G D A E V
Honey Bee Apis mellifera XP_625034 332 38858 T296 P I E V S S K T Y I L P K E K
Nematode Worm Caenorhab. elegans Q95Y71 357 41297 T319 A K Q G M V G T Q M L S A E Q
Sea Urchin Strong. purpuratus XP_793386 338 39556 T302 H R E P V V R T M V L P E E M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 26.7 81 N.A. 79.4 N.A. N.A. N.A. 51.9 54 41.5 N.A. 35.7 33.4 31.9 39.9
Protein Similarity: 100 99.3 28.7 91.1 N.A. 89.5 N.A. N.A. N.A. 68.3 72.4 57.8 N.A. 54 51.8 48.1 60.3
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 N.A. N.A. N.A. 0 66.6 20 N.A. 6.6 26.6 33.3 20
P-Site Similarity: 100 100 26.6 93.3 N.A. 100 N.A. N.A. N.A. 6.6 93.3 26.6 N.A. 26.6 53.3 53.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 0 0 9 9 0 17 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 9 0 9 0 % D
% Glu: 0 17 34 0 0 0 9 0 0 9 0 0 17 34 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 9 9 9 0 9 0 9 0 17 0 42 0 9 % G
% His: 17 0 0 0 0 9 0 0 9 9 0 0 0 0 0 % H
% Ile: 9 9 0 0 42 0 0 9 0 9 34 0 9 0 0 % I
% Lys: 0 50 9 0 9 9 59 0 0 0 0 9 9 0 9 % K
% Leu: 0 0 0 9 0 42 0 9 9 17 34 0 0 0 9 % L
% Met: 0 0 0 0 9 0 0 0 17 42 0 0 0 0 9 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 9 9 67 9 0 9 0 0 0 0 59 0 34 9 % P
% Gln: 0 0 42 0 0 0 0 0 9 0 9 0 0 9 50 % Q
% Arg: 0 9 0 0 0 0 9 9 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 9 9 0 9 9 0 0 9 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 67 0 0 0 0 9 0 0 % T
% Val: 9 0 0 9 9 25 0 0 34 9 0 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _