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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL45
All Species:
34.24
Human Site:
Y225
Identified Species:
68.48
UniProt:
Q9BRJ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRJ2
NP_115727
306
35351
Y225
T
R
Q
T
L
A
I
Y
D
R
F
G
R
L
M
Chimpanzee
Pan troglodytes
XP_512553
306
35239
Y225
T
R
Q
T
L
A
I
Y
D
R
F
G
R
L
M
Rhesus Macaque
Macaca mulatta
XP_001082116
97
11053
P23
L
G
W
W
S
R
Q
P
V
L
V
T
Q
S
S
Dog
Lupus familis
XP_850801
303
35026
Y225
T
R
Q
T
L
A
I
Y
D
R
F
G
R
L
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0Q7
306
35392
Y225
T
R
Q
T
L
A
I
Y
D
R
F
G
R
L
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423896
280
32268
N206
T
S
V
V
N
Q
G
N
L
Y
G
Q
V
T
V
Frog
Xenopus laevis
P59480
309
35333
Y225
N
K
Q
T
L
I
V
Y
D
R
F
G
R
V
M
Zebra Danio
Brachydanio rerio
NP_956601
251
29305
D176
F
G
R
L
M
L
G
D
E
E
E
P
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCX3
361
41593
Y256
S
Q
Q
M
L
A
I
Y
D
R
F
G
R
L
M
Honey Bee
Apis mellifera
XP_625034
332
38858
Y242
T
Q
Q
I
L
C
I
Y
D
R
F
G
R
V
L
Nematode Worm
Caenorhab. elegans
Q95Y71
357
41297
Y265
T
R
Q
K
L
A
V
Y
D
R
F
G
G
L
L
Sea Urchin
Strong. purpuratus
XP_793386
338
39556
Y248
T
R
Q
T
L
A
I
Y
D
R
F
G
R
I
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
26.7
81
N.A.
79.4
N.A.
N.A.
N.A.
51.9
54
41.5
N.A.
35.7
33.4
31.9
39.9
Protein Similarity:
100
99.3
28.7
91.1
N.A.
89.5
N.A.
N.A.
N.A.
68.3
72.4
57.8
N.A.
54
51.8
48.1
60.3
P-Site Identity:
100
100
0
100
N.A.
100
N.A.
N.A.
N.A.
6.6
66.6
6.6
N.A.
80
66.6
73.3
93.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
N.A.
N.A.
N.A.
13.3
86.6
33.3
N.A.
93.3
86.6
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
75
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
9
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
17
0
0
0
9
75
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
59
0
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
75
9
0
0
9
9
0
0
0
50
17
% L
% Met:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
59
% M
% Asn:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% P
% Gln:
0
17
75
0
0
9
9
0
0
0
0
9
9
0
0
% Q
% Arg:
0
50
9
0
0
9
0
0
0
75
0
0
75
0
0
% R
% Ser:
9
9
0
0
9
0
0
0
0
0
0
0
0
9
9
% S
% Thr:
67
0
0
50
0
0
0
0
0
0
0
9
0
9
0
% T
% Val:
0
0
9
9
0
0
17
0
9
0
9
0
9
17
17
% V
% Trp:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _