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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REEP2 All Species: 21.21
Human Site: S208 Identified Species: 51.85
UniProt: Q9BRK0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRK0 NP_057690.2 252 28261 S208 A D S R T E A S E D D M G D K
Chimpanzee Pan troglodytes XP_001171261 254 28427 S210 A D S R T E A S E D D M G D K
Rhesus Macaque Macaca mulatta XP_001107550 306 34165 S262 A D S R T E A S E D D M G D K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8VCD6 254 28418 S210 P D P R T E T S E D D L G D K
Rat Rattus norvegicus Q4QQW1 257 29642 S222 R E K P L S R S Q S L R V V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234440 266 29520 S217 S E I R T D P S D E D A G D K
Frog Xenopus laevis NP_001083678 263 30121 V214 E V N S E D E V Y T Q K G L R
Zebra Danio Brachydanio rerio Q4KMI4 268 30092 S217 S D S R T E H S D E D A A D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10010 229 26592 R197 P R R R A S S R S R S R S R T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LEM6 315 35085 A220 L Q T E T K E A K A S V S Q T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 79 N.A. N.A. 92.1 52.1 N.A. N.A. 68.8 50.5 66 N.A. N.A. N.A. 38.8 N.A.
Protein Similarity: 100 99.2 80 N.A. N.A. 94.8 66.5 N.A. N.A. 78.5 66.5 76.4 N.A. N.A. N.A. 59.1 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 73.3 13.3 N.A. N.A. 46.6 6.6 60 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 80 26.6 N.A. N.A. 80 26.6 80 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 0 0 0 10 0 30 10 0 10 0 20 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 0 0 20 0 0 20 40 60 0 0 60 0 % D
% Glu: 10 20 0 10 10 50 20 0 40 20 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 10 0 0 10 0 0 70 % K
% Leu: 10 0 0 0 10 0 0 0 0 0 10 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 10 0 0 10 0 % Q
% Arg: 10 10 10 70 0 0 10 10 0 10 0 20 0 10 10 % R
% Ser: 20 0 40 10 0 20 10 70 10 10 20 0 20 0 0 % S
% Thr: 0 0 10 0 70 0 10 0 0 10 0 0 0 0 20 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _