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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP2
All Species:
29.39
Human Site:
Y106
Identified Species:
71.85
UniProt:
Q9BRK0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRK0
NP_057690.2
252
28261
Y106
K
E
K
E
I
D
E
Y
I
T
Q
A
R
D
K
Chimpanzee
Pan troglodytes
XP_001171261
254
28427
Y106
K
E
K
E
I
D
E
Y
I
T
Q
A
R
D
K
Rhesus Macaque
Macaca mulatta
XP_001107550
306
34165
Y158
K
E
K
E
I
D
E
Y
I
T
Q
A
R
D
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCD6
254
28418
Y106
K
E
K
E
I
D
E
Y
I
T
Q
A
R
D
K
Rat
Rattus norvegicus
Q4QQW1
257
29642
C106
H
E
K
E
I
D
A
C
I
V
Q
A
K
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234440
266
29520
Y107
K
E
K
E
I
D
E
Y
I
T
Q
A
R
D
K
Frog
Xenopus laevis
NP_001083678
263
30121
Y106
K
E
K
E
I
D
D
Y
I
V
Q
A
K
E
K
Zebra Danio
Brachydanio rerio
Q4KMI4
268
30092
Y106
K
E
R
E
I
D
E
Y
I
T
Q
A
K
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10010
229
26592
I103
L
N
R
H
E
K
D
I
D
A
L
L
E
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEM6
315
35085
S108
H
E
N
E
I
D
R
S
L
I
E
L
R
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
79
N.A.
N.A.
92.1
52.1
N.A.
N.A.
68.8
50.5
66
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
99.2
80
N.A.
N.A.
94.8
66.5
N.A.
N.A.
78.5
66.5
76.4
N.A.
N.A.
N.A.
59.1
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
100
53.3
N.A.
N.A.
100
73.3
80
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
73.3
N.A.
N.A.
100
93.3
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
10
0
80
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
90
20
0
10
0
0
0
0
60
0
% D
% Glu:
0
90
0
90
10
0
60
0
0
0
10
0
10
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
90
0
0
10
80
10
0
0
0
0
0
% I
% Lys:
70
0
70
0
0
10
0
0
0
0
0
0
30
0
70
% K
% Leu:
10
0
0
0
0
0
0
0
10
0
10
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% Q
% Arg:
0
0
20
0
0
0
10
0
0
0
0
0
60
0
20
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
60
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _