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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC22C
All Species:
14.24
Human Site:
S137
Identified Species:
28.48
UniProt:
Q9BRL7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRL7
NP_004197.1
303
34269
S137
S
S
S
Q
M
E
C
S
L
E
K
I
Q
E
E
Chimpanzee
Pan troglodytes
XP_001139515
303
34283
S137
S
S
S
Q
M
E
C
S
L
E
K
I
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001115333
303
34463
S137
S
S
S
Q
M
E
S
S
L
E
K
I
Q
E
E
Dog
Lupus familis
XP_850413
303
34347
S137
S
S
I
Q
M
D
S
S
L
E
K
I
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXT9
303
33895
G137
S
S
S
Q
M
K
S
G
L
E
K
I
Q
E
E
Rat
Rattus norvegicus
Q642F4
307
34883
N137
R
S
L
S
T
K
I
N
L
S
D
M
Q
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509142
224
24689
R86
F
C
F
L
E
E
L
R
W
E
F
T
A
A
Y
Chicken
Gallus gallus
Q5ZJW4
215
24699
A77
C
Y
L
V
L
C
E
A
A
F
P
K
K
L
A
Frog
Xenopus laevis
NP_001087747
293
32527
D137
I
D
L
P
V
Q
S
D
P
S
P
P
P
V
F
Zebra Danio
Brachydanio rerio
Q7ZV15
215
24372
A77
C
Y
L
A
L
C
E
A
G
F
P
K
K
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796488
328
37560
K138
M
T
L
N
A
R
Q
K
Y
S
D
M
T
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AU2
218
25314
Y80
L
T
M
C
D
R
S
Y
P
K
K
L
A
F
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97
90.7
N.A.
81.5
40
N.A.
42.9
23.1
52.4
22.7
N.A.
N.A.
N.A.
N.A.
30.1
Protein Similarity:
100
100
98
96.6
N.A.
91
57.3
N.A.
51.4
36.9
71.9
37.6
N.A.
N.A.
N.A.
N.A.
49
P-Site Identity:
100
100
93.3
80
N.A.
80
26.6
N.A.
13.3
0
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
46.6
N.A.
13.3
20
13.3
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
17
9
0
0
0
17
9
17
% A
% Cys:
17
9
0
9
0
17
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
9
0
9
0
0
17
0
0
0
0
% D
% Glu:
0
0
0
0
9
34
17
0
0
50
0
0
0
42
59
% E
% Phe:
9
0
9
0
0
0
0
0
0
17
9
0
0
9
9
% F
% Gly:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
9
0
0
0
0
42
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
9
0
9
50
17
17
0
0
% K
% Leu:
9
0
42
9
17
0
9
0
50
0
0
9
0
25
0
% L
% Met:
9
0
9
0
42
0
0
0
0
0
0
17
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
17
0
25
9
9
0
0
% P
% Gln:
0
0
0
42
0
9
9
0
0
0
0
0
50
0
9
% Q
% Arg:
9
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% R
% Ser:
42
50
34
9
0
0
42
34
0
25
0
0
0
0
0
% S
% Thr:
0
17
0
0
9
0
0
0
0
0
0
9
9
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
9
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _