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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TM2D3 All Species: 14.24
Human Site: S28 Identified Species: 24.1
UniProt: Q9BRN9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRN9 NP_510883.2 247 27161 S28 L S Q F C I L S G G E Q S Q A
Chimpanzee Pan troglodytes XP_001143945 247 27155 S28 L S Q F C I L S G G E Q S Q A
Rhesus Macaque Macaca mulatta XP_001086067 247 27086 S28 L S Q F C I L S G G E Q S Q A
Dog Lupus familis XP_536173 247 27346 S28 L S Q F Y I L S G G E Q S Q P
Cat Felis silvestris
Mouse Mus musculus Q8BJ83 261 28862 A42 L E H S Q P L A Q A I K D P G
Rat Rattus norvegicus Q566R2 213 22911
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513506 249 27953 L30 E Y Q A A D S L S L E H P Q P
Chicken Gallus gallus XP_413775 252 27863 M33 L S G R G S L M T K K H S K P
Frog Xenopus laevis Q6DE06 247 27494 S28 Y V F S G R G S L S F E Y S Q
Zebra Danio Brachydanio rerio A5PLF5 244 26753 S25 C V D G Y L S S P H V G Q D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U4H5 284 31346 E65 N G N A N D N E V Y V P P L V
Honey Bee Apis mellifera XP_624179 207 23289
Nematode Worm Caenorhab. elegans Q95QZ5 195 21184
Sea Urchin Strong. purpuratus XP_781911 513 55283 G293 P V T T L A N G E P D E E L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 99.1 93.1 N.A. 82.7 26.3 N.A. 77.9 75.4 66.4 56.2 N.A. 37.3 45.3 36 25.9
Protein Similarity: 100 99.5 99.1 95.1 N.A. 87.3 37.6 N.A. 84.7 79.7 77.7 68 N.A. 52.8 58.7 49.7 32.3
P-Site Identity: 100 100 100 86.6 N.A. 13.3 0 N.A. 20 26.6 6.6 6.6 N.A. 0 0 0 0
P-Site Similarity: 100 100 100 86.6 N.A. 26.6 0 N.A. 20 40 13.3 13.3 N.A. 0 0 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 8 8 0 8 0 8 0 0 0 0 22 % A
% Cys: 8 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 15 0 0 0 0 8 0 8 8 0 % D
% Glu: 8 8 0 0 0 0 0 8 8 0 36 15 8 0 0 % E
% Phe: 0 0 8 29 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 8 8 15 0 8 8 29 29 0 8 0 0 8 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 15 0 0 0 % H
% Ile: 0 0 0 0 0 29 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 8 8 0 8 0 % K
% Leu: 43 0 0 0 8 8 43 8 8 8 0 0 0 15 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 8 0 15 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 8 0 0 8 8 0 8 15 8 36 % P
% Gln: 0 0 36 0 8 0 0 0 8 0 0 29 8 36 8 % Q
% Arg: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 36 0 15 0 8 15 43 8 8 0 0 36 8 0 % S
% Thr: 0 0 8 8 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 0 22 0 0 0 0 0 0 8 0 15 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 15 0 0 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _