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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D3
All Species:
38.79
Human Site:
T146
Identified Species:
65.64
UniProt:
Q9BRN9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRN9
NP_510883.2
247
27161
T146
T
N
S
T
S
C
M
T
V
S
C
P
R
Q
R
Chimpanzee
Pan troglodytes
XP_001143945
247
27155
T146
T
N
S
T
S
C
M
T
V
S
C
P
R
Q
R
Rhesus Macaque
Macaca mulatta
XP_001086067
247
27086
T146
T
N
S
T
S
C
M
T
V
S
C
P
R
Q
R
Dog
Lupus familis
XP_536173
247
27346
T146
S
N
S
T
S
C
M
T
V
S
C
P
R
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ83
261
28862
T160
S
N
S
T
T
C
M
T
V
A
C
P
R
Q
R
Rat
Rattus norvegicus
Q566R2
213
22911
V113
G
G
Q
A
Y
S
D
V
E
H
T
A
V
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513506
249
27953
T148
S
N
S
T
N
C
M
T
V
S
C
P
R
Q
R
Chicken
Gallus gallus
XP_413775
252
27863
T151
T
N
S
T
N
C
M
T
V
S
C
P
R
Q
R
Frog
Xenopus laevis
Q6DE06
247
27494
T146
N
L
S
S
S
C
K
T
I
S
C
P
R
Q
R
Zebra Danio
Brachydanio rerio
A5PLF5
244
26753
T143
S
N
S
S
D
C
M
T
V
S
C
P
R
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U4H5
284
31346
C183
S
C
G
Q
R
S
S
C
N
S
A
T
D
K
L
Honey Bee
Apis mellifera
XP_624179
207
23289
S106
H
Q
K
N
S
C
S
S
V
A
S
P
R
Q
Y
Nematode Worm
Caenorhab. elegans
Q95QZ5
195
21184
S95
C
E
P
A
T
N
C
S
T
S
S
T
K
L
L
Sea Urchin
Strong. purpuratus
XP_781911
513
55283
V175
T
P
A
N
N
C
H
V
Y
A
C
P
K
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.1
93.1
N.A.
82.7
26.3
N.A.
77.9
75.4
66.4
56.2
N.A.
37.3
45.3
36
25.9
Protein Similarity:
100
99.5
99.1
95.1
N.A.
87.3
37.6
N.A.
84.7
79.7
77.7
68
N.A.
52.8
58.7
49.7
32.3
P-Site Identity:
100
100
100
93.3
N.A.
80
6.6
N.A.
86.6
93.3
66.6
73.3
N.A.
6.6
40
6.6
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
80
93.3
N.A.
20
53.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
0
0
0
0
22
8
8
0
0
0
% A
% Cys:
8
8
0
0
0
79
8
8
0
0
72
0
0
0
8
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
0
0
15
8
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
15
% L
% Met:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% M
% Asn:
8
58
0
15
22
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
0
79
0
0
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
0
0
79
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
72
8
65
% R
% Ser:
36
0
65
15
43
15
15
15
0
72
15
0
0
0
0
% S
% Thr:
36
0
0
50
15
0
0
65
8
0
8
15
0
0
0
% T
% Val:
0
0
0
0
0
0
0
15
65
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _