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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TM2D3
All Species:
28.18
Human Site:
T97
Identified Species:
47.69
UniProt:
Q9BRN9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRN9
NP_510883.2
247
27161
T97
C
T
Y
G
K
P
V
T
F
D
C
A
V
K
P
Chimpanzee
Pan troglodytes
XP_001143945
247
27155
T97
C
I
Y
G
K
P
V
T
F
D
C
A
V
K
P
Rhesus Macaque
Macaca mulatta
XP_001086067
247
27086
T97
C
I
Y
G
K
P
V
T
F
D
C
A
V
K
P
Dog
Lupus familis
XP_536173
247
27346
T97
C
V
Y
G
K
P
V
T
F
D
C
T
V
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ83
261
28862
T111
C
T
Y
G
K
P
V
T
F
D
C
T
V
K
P
Rat
Rattus norvegicus
Q566R2
213
22911
D64
A
S
S
W
E
Y
S
D
P
N
S
P
V
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513506
249
27953
T99
C
V
Y
G
K
P
V
T
F
D
C
T
V
K
P
Chicken
Gallus gallus
XP_413775
252
27863
T102
C
I
Y
G
K
P
A
T
F
D
C
R
V
K
P
Frog
Xenopus laevis
Q6DE06
247
27494
T97
C
I
Y
G
K
L
V
T
F
N
C
T
A
K
N
Zebra Danio
Brachydanio rerio
A5PLF5
244
26753
N94
C
S
Y
G
R
P
H
N
Y
T
C
R
P
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U4H5
284
31346
C134
R
C
N
Y
N
H
G
C
I
Y
G
R
D
L
N
Honey Bee
Apis mellifera
XP_624179
207
23289
Y57
N
L
D
P
N
C
V
Y
G
A
V
Y
V
A
N
Nematode Worm
Caenorhab. elegans
Q95QZ5
195
21184
C46
T
C
T
F
P
G
D
C
R
I
G
D
T
V
K
Sea Urchin
Strong. purpuratus
XP_781911
513
55283
Y126
S
M
D
T
S
C
V
Y
G
R
E
Y
N
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.1
93.1
N.A.
82.7
26.3
N.A.
77.9
75.4
66.4
56.2
N.A.
37.3
45.3
36
25.9
Protein Similarity:
100
99.5
99.1
95.1
N.A.
87.3
37.6
N.A.
84.7
79.7
77.7
68
N.A.
52.8
58.7
49.7
32.3
P-Site Identity:
100
93.3
93.3
86.6
N.A.
93.3
6.6
N.A.
86.6
80
60
33.3
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
93.3
26.6
N.A.
86.6
80
66.6
60
N.A.
0
13.3
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
8
0
22
8
8
8
% A
% Cys:
65
15
0
0
0
15
0
15
0
0
65
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
8
8
0
50
0
8
8
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
58
0
0
0
0
0
0
% F
% Gly:
0
0
0
65
0
8
8
0
15
0
15
0
0
0
0
% G
% His:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
29
0
0
0
0
0
0
8
8
0
0
0
8
0
% I
% Lys:
0
0
0
0
58
0
0
0
0
0
0
0
0
58
8
% K
% Leu:
0
8
0
0
0
8
0
0
0
0
0
0
0
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
15
0
0
8
0
15
0
0
8
0
22
% N
% Pro:
0
0
0
8
8
58
0
0
8
0
0
8
8
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
0
8
8
0
22
0
8
0
% R
% Ser:
8
15
8
0
8
0
8
0
0
0
8
0
0
0
0
% S
% Thr:
8
15
8
8
0
0
0
58
0
8
0
29
8
8
8
% T
% Val:
0
15
0
0
0
0
65
0
0
0
8
0
65
8
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
8
0
8
0
15
8
8
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _