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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYGO2 All Species: 13.64
Human Site: S119 Identified Species: 25
UniProt: Q9BRQ0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ0 NP_612157.1 406 41244 S119 G Q V P P G Y S T G G G G G P
Chimpanzee Pan troglodytes XP_525221 567 57276 S281 G Q V P P G Y S T G G G G G P
Rhesus Macaque Macaca mulatta XP_001114666 405 41081 G119 G Q V P P G Y G T G V G G G P
Dog Lupus familis XP_547562 405 41099 G119 G Q V P P G Y G T G G G G G P
Cat Felis silvestris
Mouse Mus musculus Q9D0P5 417 45071 S115 P H V P P R M S S P Y C G P Y
Rat Rattus norvegicus NP_001099917 405 41066 G119 G Q V P P G Y G T G G G G G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514326 407 43303 S103 P H M P P R L S S P Y Y G P Y
Chicken Gallus gallus NP_001019862 418 44852 S116 P H M L H R V S T P Y G G S Y
Frog Xenopus laevis NP_001082328 389 41400 T101 G A M P H Q M T P G Y P G G P
Zebra Danio Brachydanio rerio NP_001028283 571 56263 N247 G G M G G G M N M M G M G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9W8 815 80474 N211 V G L P P H M N H G R P G G P
Honey Bee Apis mellifera XP_394285 396 41911 S132 P M N N M G H S M G S P M G G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791313 224 24117
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.2 98.5 96.8 N.A. 36.4 96.3 N.A. 37.3 33.9 67.7 33.6 N.A. 21.3 23.3 N.A. 24.6
Protein Similarity: 100 71.2 98.7 97 N.A. 48.2 97 N.A. 48.1 44.2 74.8 39.5 N.A. 27.9 34.7 N.A. 35.4
P-Site Identity: 100 100 86.6 93.3 N.A. 33.3 93.3 N.A. 26.6 26.6 40 33.3 N.A. 40 26.6 N.A. 0
P-Site Similarity: 100 100 86.6 93.3 N.A. 40 93.3 N.A. 40 33.3 53.3 46.6 N.A. 53.3 33.3 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 54 16 0 8 8 54 0 24 0 62 39 47 85 70 16 % G
% His: 0 24 0 0 16 8 8 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % L
% Met: 0 8 31 0 8 0 31 0 16 8 0 8 8 0 0 % M
% Asn: 0 0 8 8 0 0 0 16 0 0 0 0 0 0 0 % N
% Pro: 31 0 0 70 62 0 0 0 8 24 0 24 0 16 54 % P
% Gln: 0 39 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 24 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 47 16 0 8 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 8 47 0 0 0 0 0 0 % T
% Val: 8 0 47 0 0 0 8 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 39 0 0 0 31 8 0 0 24 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _