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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORAI3
All Species:
7.88
Human Site:
S216
Identified Species:
19.26
UniProt:
Q9BRQ5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ5
NP_689501.1
295
31499
S216
N
L
P
R
S
S
A
S
A
A
P
S
Q
A
E
Chimpanzee
Pan troglodytes
XP_528664
301
32521
Q233
T
S
G
I
T
P
G
Q
A
A
A
I
A
S
T
Rhesus Macaque
Macaca mulatta
XP_001111639
295
31645
S216
N
L
P
P
S
S
A
S
T
A
P
S
Q
A
E
Dog
Lupus familis
XP_849021
295
31488
A216
K
P
S
S
T
P
V
A
P
S
Q
A
E
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q6P8G8
290
31340
S216
S
S
A
S
I
T
T
S
Q
Q
P
S
K
A
C
Rat
Rattus norvegicus
Q6AXR8
290
31293
T216
S
S
A
S
V
A
T
T
Q
Q
P
P
K
A
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507478
312
32775
A217
L
A
A
S
P
S
A
A
S
A
S
A
P
P
S
Chicken
Gallus gallus
Q5ZLW2
257
28936
Q198
P
S
G
H
A
G
W
Q
A
A
L
V
S
T
I
Frog
Xenopus laevis
Q6NZI6
257
28909
L201
N
A
G
W
N
S
A
L
V
S
T
I
I
M
V
Zebra Danio
Brachydanio rerio
Q6TLE6
222
24614
G169
T
S
I
M
V
P
F
G
L
V
F
I
V
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
96.9
89.1
N.A.
87.4
89.8
N.A.
80.4
53.2
54.2
45
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.4
97.2
92.8
N.A.
90.8
92.5
N.A.
84.6
67.4
68.4
54.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
86.6
0
N.A.
26.6
13.3
N.A.
20
13.3
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
86.6
33.3
N.A.
46.6
40
N.A.
40
20
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
30
0
10
10
40
20
30
50
10
20
10
40
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
20
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
30
0
0
10
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
0
0
0
0
30
10
0
10
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% K
% Leu:
10
20
0
0
0
0
0
10
10
0
10
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
30
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
20
10
10
30
0
0
10
0
40
10
10
20
0
% P
% Gln:
0
0
0
0
0
0
0
20
20
20
10
0
20
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
50
10
40
20
40
0
30
10
20
10
30
10
10
10
% S
% Thr:
20
0
0
0
20
10
20
10
10
0
10
0
0
10
10
% T
% Val:
0
0
0
0
20
0
10
0
10
10
0
10
10
0
10
% V
% Trp:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _