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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORAI3 All Species: 22.73
Human Site: S269 Identified Species: 55.56
UniProt: Q9BRQ5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ5 NP_689501.1 295 31499 S269 F A L H F Y R S L V A H K T D
Chimpanzee Pan troglodytes XP_528664 301 32521 F270 S H K T D R Q F Q E L N E L A
Rhesus Macaque Macaca mulatta XP_001111639 295 31645 S269 F A L H F Y R S L V A H K T D
Dog Lupus familis XP_849021 295 31488 S269 F A L H F Y R S L V A H K T D
Cat Felis silvestris
Mouse Mus musculus Q6P8G8 290 31340 S264 F A L H F Y R S L V A H K T D
Rat Rattus norvegicus Q6AXR8 290 31293 S264 F A L H F Y R S L V A H K T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507478 312 32775 S286 F A L H F Y R S L V A H K T D
Chicken Gallus gallus Q5ZLW2 257 28936 H241 N R E I E E L H K L K V Q L D
Frog Xenopus laevis Q6NZI6 257 28909 H241 H Q E I E E L H K L K V Q L D
Zebra Danio Brachydanio rerio Q6TLE6 222 24614 D206 E D L Q N E L D H R E E V S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47.8 96.9 89.1 N.A. 87.4 89.8 N.A. 80.4 53.2 54.2 45 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 62.4 97.2 92.8 N.A. 90.8 92.5 N.A. 84.6 67.4 68.4 54.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 100 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 20 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 60 0 0 0 0 0 0 0 0 60 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 80 % D
% Glu: 10 0 20 0 20 30 0 0 0 10 10 10 10 0 0 % E
% Phe: 60 0 0 0 60 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 10 0 60 0 0 0 20 10 0 0 60 0 0 0 % H
% Ile: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 20 0 20 0 60 0 0 % K
% Leu: 0 0 70 0 0 0 30 0 60 20 10 0 0 30 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 10 0 0 10 0 10 0 0 0 20 0 0 % Q
% Arg: 0 10 0 0 0 10 60 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 0 60 0 0 0 0 0 10 0 % S
% Thr: 0 0 0 10 0 0 0 0 0 0 0 0 0 60 10 % T
% Val: 0 0 0 0 0 0 0 0 0 60 0 20 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _