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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIFM2
All Species:
21.21
Human Site:
S258
Identified Species:
42.42
UniProt:
Q9BRQ8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRQ8
NP_116186.1
373
40527
S258
A
Y
R
K
A
F
E
S
R
L
A
S
S
G
A
Chimpanzee
Pan troglodytes
XP_001170630
373
40520
S258
A
Y
R
K
A
F
E
S
R
L
A
S
S
G
A
Rhesus Macaque
Macaca mulatta
XP_001108666
373
40507
S258
A
Y
R
N
A
F
E
S
R
L
A
S
S
G
A
Dog
Lupus familis
XP_536378
373
40566
G258
A
Y
H
S
A
F
D
G
H
L
A
S
N
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUE4
373
40616
S258
A
Y
R
S
A
F
E
S
R
L
A
S
N
G
A
Rat
Rattus norvegicus
NP_001132955
373
40672
S258
A
Y
R
S
A
F
E
S
R
L
A
S
N
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421597
373
40601
D257
A
Y
A
T
A
F
G
D
K
L
A
S
N
G
A
Frog
Xenopus laevis
Q6GLW8
374
40759
D258
S
Y
R
S
A
L
G
D
K
M
A
E
D
G
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781398
553
60494
S255
A
Y
A
E
E
L
G
S
K
M
D
A
R
G
S
Poplar Tree
Populus trichocarpa
XP_002299779
362
39920
S244
L
E
G
T
I
L
N
S
N
L
D
S
R
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXR9
519
56898
L369
E
P
S
G
P
N
V
L
P
L
N
A
R
G
Q
Baker's Yeast
Sacchar. cerevisiae
P32340
513
57231
E356
D
L
F
K
K
I
P
E
Q
N
S
S
K
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.3
85.5
N.A.
90.3
90.6
N.A.
N.A.
69.7
61.5
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
100
99.7
99.1
94
N.A.
96.2
96.7
N.A.
N.A.
86
81.8
N.A.
N.A.
N.A.
N.A.
N.A.
43.7
P-Site Identity:
100
100
93.3
60
N.A.
86.6
86.6
N.A.
N.A.
60
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
93.3
93.3
N.A.
N.A.
73.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
31.3
N.A.
N.A.
22.1
23
N.A.
Protein Similarity:
51.2
N.A.
N.A.
37.3
38.7
N.A.
P-Site Identity:
26.6
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
17
0
67
0
0
0
0
0
67
17
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
17
0
0
17
0
9
0
0
% D
% Glu:
9
9
0
9
9
0
42
9
0
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
0
59
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
0
0
25
9
0
0
0
0
0
92
9
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
25
9
0
0
0
25
0
0
0
9
0
0
% K
% Leu:
9
9
0
0
0
25
0
9
0
75
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
9
0
9
9
9
0
34
0
0
% N
% Pro:
0
9
0
0
9
0
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% Q
% Arg:
0
0
50
0
0
0
0
0
42
0
0
0
25
9
9
% R
% Ser:
9
0
9
34
0
0
0
59
0
0
9
75
25
0
17
% S
% Thr:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _