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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AIFM2 All Species: 31.52
Human Site: Y296 Identified Species: 63.03
UniProt: Q9BRQ8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRQ8 NP_116186.1 373 40527 Y296 V R T P K M A Y L A G L H A N
Chimpanzee Pan troglodytes XP_001170630 373 40520 Y296 V R T P K M A Y L A G L H A N
Rhesus Macaque Macaca mulatta XP_001108666 373 40507 Y296 V R T P K M A Y L A G L H A N
Dog Lupus familis XP_536378 373 40566 Y296 V K E P K M A Y H A G L H A S
Cat Felis silvestris
Mouse Mus musculus Q8BUE4 373 40616 Y296 T K E P K M A Y H A G L H A N
Rat Rattus norvegicus NP_001132955 373 40672 Y296 I K E P K M A Y H A G L H A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421597 373 40601 Y295 L K E P K M A Y H A E L H A N
Frog Xenopus laevis Q6GLW8 374 40759 Y296 I N E P K M A Y Y A G I H A R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781398 553 60494 Y293 A D I Q K M A Y R A G E Q G K
Poplar Tree Populus trichocarpa XP_002299779 362 39920 Y282 V P E I K Q G Y L A Q K H A L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GXR9 519 56898 I407 L R D S N G K I L P T T A Q V
Baker's Yeast Sacchar. cerevisiae P32340 513 57231 Q394 A G L P P T A Q V A H Q E A E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.3 85.5 N.A. 90.3 90.6 N.A. N.A. 69.7 61.5 N.A. N.A. N.A. N.A. N.A. 27.8
Protein Similarity: 100 99.7 99.1 94 N.A. 96.2 96.7 N.A. N.A. 86 81.8 N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: 100 100 100 73.3 N.A. 73.3 73.3 N.A. N.A. 66.6 60 N.A. N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 86.6 N.A. 80 86.6 N.A. N.A. 80 73.3 N.A. N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 31.3 N.A. N.A. 22.1 23 N.A.
Protein Similarity: 51.2 N.A. N.A. 37.3 38.7 N.A.
P-Site Identity: 46.6 N.A. N.A. 13.3 26.6 N.A.
P-Site Similarity: 46.6 N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 84 0 0 92 0 0 9 84 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 50 0 0 0 0 0 0 0 9 9 9 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 9 9 0 0 0 67 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 34 0 9 0 75 0 0 % H
% Ile: 17 0 9 9 0 0 0 9 0 0 0 9 0 0 0 % I
% Lys: 0 34 0 0 84 0 9 0 0 0 0 9 0 0 9 % K
% Leu: 17 0 9 0 0 0 0 0 42 0 0 59 0 0 9 % L
% Met: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 50 % N
% Pro: 0 9 0 75 9 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 9 0 9 0 0 9 9 9 9 0 % Q
% Arg: 0 34 0 0 0 0 0 0 9 0 0 0 0 0 9 % R
% Ser: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % S
% Thr: 9 0 25 0 0 9 0 0 0 0 9 9 0 0 0 % T
% Val: 42 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _