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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf125 All Species: 13.03
Human Site: Y378 Identified Species: 35.83
UniProt: Q9BRR3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRR3 NP_115718.1 403 46588 Y378 R A K G E R A Y V V E P N L V
Chimpanzee Pan troglodytes XP_001135933 250 29015 V226 A K G E R A Y V V E P N L V K
Rhesus Macaque Macaca mulatta XP_001110845 395 45597 L370 D M A L Y S L L R A K G E R A
Dog Lupus familis XP_538758 403 46461 Y378 R A K G E R A Y V V E P N L V
Cat Felis silvestris
Mouse Mus musculus Q91YV9 403 46573 Y378 R A K G E R A Y V V E P N L V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510718 426 48967 F401 R V K G E R A F V V E P N L V
Chicken Gallus gallus XP_430497 395 45959 Y370 R T K G E N A Y V V E P N L V
Frog Xenopus laevis NP_001108291 365 41785 P341 E W A W A I E P N M V K H V G
Zebra Danio Brachydanio rerio NP_001070809 396 45385 A369 R S T P G E K A H S V E P N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62 98 97.2 N.A. 98.2 N.A. N.A. 65.7 62.7 44.4 41.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 62 98 98.2 N.A. 99.5 N.A. N.A. 79.1 75.6 57.5 60.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 100 N.A. 100 N.A. N.A. 86.6 86.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 6.6 100 N.A. 100 N.A. N.A. 93.3 86.6 20 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 34 23 0 12 12 56 12 0 12 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 12 56 12 12 0 0 12 56 12 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 0 0 12 56 12 0 0 0 0 0 0 12 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 12 56 0 0 0 12 0 0 0 12 12 0 0 12 % K
% Leu: 0 0 0 12 0 0 12 12 0 0 0 0 12 56 12 % L
% Met: 0 12 0 0 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 12 0 0 12 56 12 0 % N
% Pro: 0 0 0 12 0 0 0 12 0 0 12 56 12 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 67 0 0 0 12 45 0 0 12 0 0 0 0 12 0 % R
% Ser: 0 12 0 0 0 12 0 0 0 12 0 0 0 0 0 % S
% Thr: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 0 12 67 56 23 0 0 23 56 % V
% Trp: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 12 45 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _