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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIOK1 All Species: 46.97
Human Site: S477 Identified Species: 79.49
UniProt: Q9BRS2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRS2 NP_113668.2 568 65583 S477 T G L K K D L S G V Q K V P A
Chimpanzee Pan troglodytes XP_527225 568 65487 S477 T G L K K D L S G V Q K V P A
Rhesus Macaque Macaca mulatta XP_001084661 567 65490 S476 T G L K K D L S G V Q K V P A
Dog Lupus familis XP_535878 569 65688 S478 T G L K K D L S G V Q K V P A
Cat Felis silvestris
Mouse Mus musculus Q922Q2 567 64892 S476 M G L K K D L S G V Q K V P A
Rat Rattus norvegicus XP_214454 566 65166 S475 T G L K K D L S G V Q K V P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514154 620 71362 S529 T G L K K D L S G V Q K V P E
Chicken Gallus gallus XP_418958 569 65247 S480 T G L K K D L S G V Q K I P A
Frog Xenopus laevis NP_001116165 542 62486 S449 T G L K K D L S G A E T V P A
Zebra Danio Brachydanio rerio NP_998160 552 63898 S473 T G L R K D L S G V Q T V P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648489 585 67475 D492 T G L T S D L D V Q Q K P D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793660 539 63109 S430 T G L K G D L S G I Q E D P A
Poplar Tree Populus trichocarpa XP_002322256 559 63327 S452 T G L K E A L S N S S A A Q Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12196 484 56104 S417 D D E E D G S S G S E E D D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.5 89.6 N.A. 80.2 81.5 N.A. 73 75.2 70.4 69.7 N.A. 47 N.A. N.A. 50.1
Protein Similarity: 100 98.9 96.8 94.9 N.A. 88 89.7 N.A. 80.9 84.1 80.6 82.2 N.A. 64.2 N.A. N.A. 66
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 93.3 93.3 80 80 N.A. 46.6 N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 100 N.A. 93.3 100 86.6 93.3 N.A. 46.6 N.A. N.A. 86.6
Percent
Protein Identity: 41 N.A. N.A. N.A. 32 N.A.
Protein Similarity: 60.7 N.A. N.A. N.A. 49.3 N.A.
P-Site Identity: 40 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 8 0 8 8 0 65 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 86 0 8 0 0 0 0 15 15 0 % D
% Glu: 0 0 8 8 8 0 0 0 0 0 15 15 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 93 0 0 8 8 0 0 86 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 0 0 79 72 0 0 0 0 0 0 65 0 0 0 % K
% Leu: 0 0 93 0 0 0 93 0 0 0 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 79 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 79 0 0 8 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 8 0 8 93 0 15 8 0 0 0 8 % S
% Thr: 86 0 0 8 0 0 0 0 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 65 0 0 65 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _