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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIOK1
All Species:
38.48
Human Site:
Y440
Identified Species:
65.13
UniProt:
Q9BRS2
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRS2
NP_113668.2
568
65583
Y440
T
L
N
E
V
K
N
Y
E
R
D
M
D
I
I
Chimpanzee
Pan troglodytes
XP_527225
568
65487
Y440
T
L
N
E
V
K
N
Y
E
R
D
M
D
I
I
Rhesus Macaque
Macaca mulatta
XP_001084661
567
65490
Y439
T
L
N
E
V
K
H
Y
E
R
D
M
D
L
I
Dog
Lupus familis
XP_535878
569
65688
Y441
T
L
N
E
V
K
N
Y
E
R
D
I
D
I
M
Cat
Felis silvestris
Mouse
Mus musculus
Q922Q2
567
64892
Y439
T
L
N
E
V
K
N
Y
E
R
D
V
D
I
M
Rat
Rattus norvegicus
XP_214454
566
65166
Y438
T
L
N
E
V
K
N
Y
E
R
D
V
D
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514154
620
71362
Y492
T
L
N
E
V
K
N
Y
E
R
D
V
D
I
M
Chicken
Gallus gallus
XP_418958
569
65247
Y443
T
L
T
E
V
K
N
Y
E
R
D
V
D
I
M
Frog
Xenopus laevis
NP_001116165
542
62486
F412
T
L
N
E
V
K
N
F
E
R
D
V
D
T
M
Zebra Danio
Brachydanio rerio
NP_998160
552
63898
Y436
T
L
N
E
V
T
H
Y
E
R
D
V
D
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648489
585
67475
F464
R
L
D
E
V
R
H
F
E
R
D
V
A
K
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793660
539
63109
Y402
K
L
E
E
V
K
H
Y
E
K
E
I
V
K
A
Poplar Tree
Populus trichocarpa
XP_002322256
559
63327
A423
T
L
D
D
V
K
H
A
E
E
D
V
N
R
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12196
484
56104
Q391
R
N
F
A
A
S
E
Q
F
E
F
D
N
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
94.5
89.6
N.A.
80.2
81.5
N.A.
73
75.2
70.4
69.7
N.A.
47
N.A.
N.A.
50.1
Protein Similarity:
100
98.9
96.8
94.9
N.A.
88
89.7
N.A.
80.9
84.1
80.6
82.2
N.A.
64.2
N.A.
N.A.
66
P-Site Identity:
100
100
86.6
86.6
N.A.
86.6
86.6
N.A.
86.6
80
73.3
66.6
N.A.
40
N.A.
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
73.3
N.A.
N.A.
66.6
Percent
Protein Identity:
41
N.A.
N.A.
N.A.
32
N.A.
Protein Similarity:
60.7
N.A.
N.A.
N.A.
49.3
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
0
0
0
8
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
8
0
0
0
0
0
0
86
8
72
0
8
% D
% Glu:
0
0
8
86
0
0
8
0
93
15
8
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
15
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
15
0
50
29
% I
% Lys:
8
0
0
0
0
79
0
0
0
8
0
0
0
15
0
% K
% Leu:
0
93
0
0
0
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
22
0
0
50
% M
% Asn:
0
8
65
0
0
0
58
0
0
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
8
0
0
0
79
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
79
0
8
0
0
8
0
0
0
0
0
0
0
15
0
% T
% Val:
0
0
0
0
93
0
0
0
0
0
0
58
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _