Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS4 All Species: 31.52
Human Site: S120 Identified Species: 49.52
UniProt: Q9BRT9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRT9 NP_115712.1 223 26047 S120 T R P E G E P S S L S P E E L
Chimpanzee Pan troglodytes XP_001138293 223 26042 S120 T R P E G E P S S L S P E E L
Rhesus Macaque Macaca mulatta XP_001094432 223 26084 S120 T R P E G E P S S L S P E E L
Dog Lupus familis XP_539958 292 33552 S188 T P R E G E L S S L S P E E L
Cat Felis silvestris
Mouse Mus musculus Q99LZ3 223 25942 S120 V R S E G E P S S L S P E E F
Rat Rattus norvegicus Q499W2 223 26043 S120 T R P A G E P S S L S P E E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510297 388 43006 S285 T R S E G D P S S L S P E E F
Chicken Gallus gallus XP_001234216 246 28024 S143 S R A K G E P S I L S P E E F
Frog Xenopus laevis NP_001084702 221 25526 P118 S R G E G E P P H L S P E E F
Zebra Danio Brachydanio rerio NP_001003546 217 25089 S114 S R A D G D P S F L S P E E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651457 228 26107 K131 E S R E P D D K R L S P E E T
Honey Bee Apis mellifera XP_001120752 219 25421 C120 A N R S S E E C Y L T V A E L
Nematode Worm Caenorhab. elegans NP_507905 224 25660 D123 R K E E G K S D L L S E S E M
Sea Urchin Strong. purpuratus XP_001189789 225 26139 K121 T R G P D E P K M L S P E E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03406 294 33929 D173 N S L I S L T D L L S K D E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 68.1 N.A. 87.8 88.7 N.A. 49.4 73.1 71.7 71.3 N.A. 40.3 43.9 33.9 56.8
Protein Similarity: 100 100 99.5 72.2 N.A. 93.7 93.7 N.A. 54.3 83.7 84.7 88.7 N.A. 64.4 68.1 58.9 74.6
P-Site Identity: 100 100 100 80 N.A. 80 86.6 N.A. 80 66.6 66.6 60 N.A. 40 26.6 33.3 60
P-Site Similarity: 100 100 100 80 N.A. 80 86.6 N.A. 86.6 80 73.3 80 N.A. 46.6 33.3 53.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 14 7 0 0 0 0 0 0 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 7 20 7 14 0 0 0 0 7 0 0 % D
% Glu: 7 0 7 60 0 67 7 0 0 0 0 7 80 100 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 47 % F
% Gly: 0 0 14 0 74 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 7 % I
% Lys: 0 7 0 7 0 7 0 14 0 0 0 7 0 0 0 % K
% Leu: 0 0 7 0 0 7 7 0 14 100 0 0 0 0 34 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 27 7 7 0 67 7 0 0 0 80 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 67 20 0 0 0 0 0 7 0 0 0 0 0 0 % R
% Ser: 20 14 14 7 14 0 7 60 47 0 94 0 7 0 0 % S
% Thr: 47 0 0 0 0 0 7 0 0 0 7 0 0 0 7 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _