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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS4 All Species: 45.45
Human Site: S169 Identified Species: 71.43
UniProt: Q9BRT9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRT9 NP_115712.1 223 26047 S169 V P K P D L D S Y V F L R V R
Chimpanzee Pan troglodytes XP_001138293 223 26042 S169 V P K P D L D S Y V F L R V R
Rhesus Macaque Macaca mulatta XP_001094432 223 26084 S169 V P K P D L D S Y V F L R V R
Dog Lupus familis XP_539958 292 33552 S238 V P K P D L D S Y V F L R V K
Cat Felis silvestris
Mouse Mus musculus Q99LZ3 223 25942 S169 V P K P D L D S Y V F L R V K
Rat Rattus norvegicus Q499W2 223 26043 S169 V P K P D L D S Y V F L R V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510297 388 43006 S334 V P K P D L D S Y V F L R V K
Chicken Gallus gallus XP_001234216 246 28024 S192 V P K P N L D S F V F L R V L
Frog Xenopus laevis NP_001084702 221 25526 S167 V P K P N L D S F V F L R V K
Zebra Danio Brachydanio rerio NP_001003546 217 25089 S163 V P E P C L D S F V F L R V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651457 228 26107 T174 E A E Q R I V T P N L M S H V
Honey Bee Apis mellifera XP_001120752 219 25421 P165 V N K L T V K P N M K A Y V F
Nematode Worm Caenorhab. elegans NP_507905 224 25660 D168 V P R G D H D D V M V Y A K V
Sea Urchin Strong. purpuratus XP_001189789 225 26139 S170 V P K P N L D S Y V F L R A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03406 294 33929 K226 I D E P D W N K F V F I H V N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 68.1 N.A. 87.8 88.7 N.A. 49.4 73.1 71.7 71.3 N.A. 40.3 43.9 33.9 56.8
Protein Similarity: 100 100 99.5 72.2 N.A. 93.7 93.7 N.A. 54.3 83.7 84.7 88.7 N.A. 64.4 68.1 58.9 74.6
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 80 80 73.3 N.A. 0 20 26.6 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 93.3 N.A. 26.6 33.3 40 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 0 0 0 7 7 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 60 0 80 7 0 0 0 0 0 0 0 % D
% Glu: 7 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 27 0 80 0 0 0 7 % F
% Gly: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 7 7 0 % H
% Ile: 7 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % I
% Lys: 0 0 74 0 0 0 7 7 0 0 7 0 0 7 40 % K
% Leu: 0 0 0 7 0 74 0 0 0 0 7 74 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 14 0 7 0 0 0 % M
% Asn: 0 7 0 0 20 0 7 0 7 7 0 0 0 0 14 % N
% Pro: 0 80 0 80 0 0 0 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 7 0 0 0 0 0 0 0 74 0 20 % R
% Ser: 0 0 0 0 0 0 0 74 0 0 0 0 7 0 0 % S
% Thr: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % T
% Val: 87 0 0 0 0 7 7 0 7 80 7 0 0 80 14 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 54 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _