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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS4 All Species: 36.06
Human Site: T113 Identified Species: 56.67
UniProt: Q9BRT9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRT9 NP_115712.1 223 26047 T113 H V L E K E K T R P E G E P S
Chimpanzee Pan troglodytes XP_001138293 223 26042 T113 H V L E K E K T R P E G E P S
Rhesus Macaque Macaca mulatta XP_001094432 223 26084 T113 H V L E K E K T R P E G E P S
Dog Lupus familis XP_539958 292 33552 T181 H I L E K E K T P R E G E L S
Cat Felis silvestris
Mouse Mus musculus Q99LZ3 223 25942 V113 H I L E K E K V R S E G E P S
Rat Rattus norvegicus Q499W2 223 26043 T113 H I L E K E K T R P A G E P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510297 388 43006 T278 H V L E K E K T R S E G D P S
Chicken Gallus gallus XP_001234216 246 28024 S136 H V L E K E K S R A K G E P S
Frog Xenopus laevis NP_001084702 221 25526 S111 H I L E K E K S R G E G E P P
Zebra Danio Brachydanio rerio NP_001003546 217 25089 S107 H V L E K E K S R A D G D P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651457 228 26107 E124 Q H I L N Q E E S R E P D D K
Honey Bee Apis mellifera XP_001120752 219 25421 A113 I H I L S E E A N R S S E E C
Nematode Worm Caenorhab. elegans NP_507905 224 25660 R116 A I D Q H K K R K E E G K S D
Sea Urchin Strong. purpuratus XP_001189789 225 26139 T114 H T L H K E S T R G P D E P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03406 294 33929 N166 R Q L N E D E N S L I S L T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.6 68.1 N.A. 87.8 88.7 N.A. 49.4 73.1 71.7 71.3 N.A. 40.3 43.9 33.9 56.8
Protein Similarity: 100 100 99.5 72.2 N.A. 93.7 93.7 N.A. 54.3 83.7 84.7 88.7 N.A. 64.4 68.1 58.9 74.6
P-Site Identity: 100 100 100 73.3 N.A. 80 86.6 N.A. 86.6 80 73.3 73.3 N.A. 6.6 13.3 20 53.3
P-Site Similarity: 100 100 100 80 N.A. 86.6 93.3 N.A. 93.3 93.3 86.6 93.3 N.A. 33.3 26.6 53.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 7 0 14 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 7 0 0 7 0 0 0 0 7 7 20 7 14 % D
% Glu: 0 0 0 67 7 80 20 7 0 7 60 0 67 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 14 0 74 0 0 0 % G
% His: 74 14 0 7 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 34 14 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 74 7 74 0 7 0 7 0 7 0 14 % K
% Leu: 0 0 80 14 0 0 0 0 0 7 0 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 0 7 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 7 27 7 7 0 67 7 % P
% Gln: 7 7 0 7 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 7 67 20 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 7 20 14 14 7 14 0 7 60 % S
% Thr: 0 7 0 0 0 0 0 47 0 0 0 0 0 7 0 % T
% Val: 0 40 0 0 0 0 0 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _