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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIKE1
All Species:
32.12
Human Site:
S135
Identified Species:
70.67
UniProt:
Q9BRV8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRV8
NP_001095866.1
207
23721
S135
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Chimpanzee
Pan troglodytes
XP_001149692
199
22949
S127
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Rhesus Macaque
Macaca mulatta
XP_001111696
207
23730
S135
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Dog
Lupus familis
XP_540248
207
23682
S135
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPR7
207
23503
S135
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Rat
Rattus norvegicus
Q5FWT9
207
23559
S135
L
K
A
H
Q
S
H
S
A
E
I
E
S
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521621
154
18022
I113
D
D
H
Q
F
C
K
I
Q
E
K
L
A
Q
L
Chicken
Gallus gallus
Q5ZKJ4
217
25179
S133
M
K
L
K
E
Q
H
S
K
E
L
Q
V
H
V
Frog
Xenopus laevis
Q6GP65
205
23842
S135
L
E
A
H
K
T
F
S
S
D
L
E
C
Q
I
Zebra Danio
Brachydanio rerio
Q7T338
215
24988
T131
T
Q
L
R
E
Q
H
T
N
E
M
Q
A
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786805
249
28580
D130
L
A
N
Q
K
T
L
D
F
E
Q
D
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.5
98
N.A.
91.7
90.8
N.A.
67.1
49.3
64.2
44.6
N.A.
N.A.
N.A.
N.A.
33.7
Protein Similarity:
100
96.1
100
99.5
N.A.
96.1
95.6
N.A.
71
67.7
83.5
68.8
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
26.6
46.6
20
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
60
86.6
60
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
64
0
0
0
0
0
55
0
0
0
19
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
10
0
0
0
0
0
10
0
10
0
10
0
0
0
% D
% Glu:
0
10
0
0
19
0
0
0
0
91
0
64
0
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
64
0
0
73
0
0
0
0
0
0
19
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
55
0
0
0
73
% I
% Lys:
0
64
0
10
19
0
10
0
10
0
10
0
0
0
0
% K
% Leu:
73
0
19
0
0
0
10
0
0
0
19
10
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
10
0
19
55
19
0
0
10
0
10
19
0
73
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
55
0
73
10
0
0
0
55
0
0
% S
% Thr:
10
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _