KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIKE1
All Species:
21.21
Human Site:
S198
Identified Species:
46.67
UniProt:
Q9BRV8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRV8
NP_001095866.1
207
23721
S198
L
Q
A
R
K
E
N
S
M
D
T
A
S
Q
A
Chimpanzee
Pan troglodytes
XP_001149692
199
22949
S190
L
Q
A
R
K
E
N
S
M
D
T
A
S
Q
A
Rhesus Macaque
Macaca mulatta
XP_001111696
207
23730
S198
L
Q
A
R
K
E
N
S
M
D
T
A
S
Q
A
Dog
Lupus familis
XP_540248
207
23682
S198
L
Q
V
R
K
E
N
S
M
D
T
A
S
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CPR7
207
23503
S198
L
Q
V
G
K
E
S
S
V
A
P
A
S
Q
T
Rat
Rattus norvegicus
Q5FWT9
207
23559
S198
L
Q
V
G
K
E
S
S
V
A
P
E
A
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521621
154
18022
M146
Q
M
K
K
E
E
S
M
D
S
A
S
Q
D
T
Chicken
Gallus gallus
Q5ZKJ4
217
25179
D196
F
L
N
L
K
K
E
D
A
S
E
S
T
S
L
Frog
Xenopus laevis
Q6GP65
205
23842
K195
N
E
S
L
R
S
S
K
K
E
S
E
W
N
F
Zebra Danio
Brachydanio rerio
Q7T338
215
24988
D194
F
L
L
L
K
R
D
D
T
S
D
S
T
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786805
249
28580
S185
L
R
E
L
L
Q
I
S
R
T
T
Q
A
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.5
98
N.A.
91.7
90.8
N.A.
67.1
49.3
64.2
44.6
N.A.
N.A.
N.A.
N.A.
33.7
Protein Similarity:
100
96.1
100
99.5
N.A.
96.1
95.6
N.A.
71
67.7
83.5
68.8
N.A.
N.A.
N.A.
N.A.
57
P-Site Identity:
100
100
100
93.3
N.A.
53.3
40
N.A.
6.6
6.6
0
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
60
N.A.
33.3
26.6
40
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
0
0
0
0
0
10
19
10
46
19
0
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
19
10
37
10
0
0
10
0
% D
% Glu:
0
10
10
0
10
64
10
0
0
10
10
19
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
73
10
0
10
10
0
0
0
0
0
0
% K
% Leu:
64
19
10
37
10
0
0
0
0
0
0
0
0
0
19
% L
% Met:
0
10
0
0
0
0
0
10
37
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
37
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% P
% Gln:
10
55
0
0
0
10
0
0
0
0
0
10
10
55
0
% Q
% Arg:
0
10
0
37
10
10
0
0
10
0
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
10
37
64
0
28
10
28
46
19
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
46
0
19
0
28
% T
% Val:
0
0
28
0
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _