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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS3 All Species: 30.3
Human Site: S137 Identified Species: 66.67
UniProt: Q9BRX5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRX5 NP_001119601.1 216 24535 S137 E N A D I S Q S L L Q T F I G
Chimpanzee Pan troglodytes XP_511004 216 24530 S137 E N A D I S Q S L L Q T F I G
Rhesus Macaque Macaca mulatta XP_001101868 216 24490 S137 E N A D I S Q S L L Q T F I G
Dog Lupus familis XP_544380 216 24342 S137 E N A D I S E S L L Q T F I G
Cat Felis silvestris
Mouse Mus musculus Q9CY94 216 24558 S137 E N A D I S Q S L L K T F I G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507732 216 24152 T137 E N T K I S Q T L L Q T F I G
Chicken Gallus gallus XP_413991 214 23844 C135 E N P E I A Q C I L Q T F I N
Frog Xenopus laevis NP_001080618 210 23901 T131 E N P E I A K T I L Q T F V G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781737 212 24582 S130 E S E D I A K S L I E T Y I N
Poplar Tree Populus trichocarpa XP_002316214 184 20940 G109 P L C D K T I G L L L P Y A F
Maize Zea mays NP_001147271 194 21689 F119 G L F L R Y A F T S R Y K E V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 94.4 N.A. 89.3 N.A. N.A. 81.9 75.4 72.6 N.A. N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 100 99.5 97.6 N.A. 94.4 N.A. N.A. 88.8 88.4 86.5 N.A. N.A. N.A. N.A. N.A. 67.5
P-Site Identity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 80 60 53.3 N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 80 93.3 N.A. N.A. N.A. N.A. N.A. 86.6
Percent
Protein Identity: 25 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: 42.5 44.4 N.A. N.A. N.A. N.A.
P-Site Identity: 20 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 46 0 0 28 10 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 82 0 10 19 0 0 10 0 0 0 10 0 0 10 0 % E
% Phe: 0 0 10 0 0 0 0 10 0 0 0 0 73 0 10 % F
% Gly: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 64 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 82 0 10 0 19 10 0 0 0 73 0 % I
% Lys: 0 0 0 10 10 0 19 0 0 0 10 0 10 0 0 % K
% Leu: 0 19 0 10 0 0 0 0 73 82 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 73 0 0 0 0 0 0 0 0 0 0 0 0 19 % N
% Pro: 10 0 19 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 55 0 0 0 64 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 10 0 0 0 55 0 55 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 0 0 10 0 19 10 0 0 82 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 10 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _