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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS3 All Species: 29.39
Human Site: S195 Identified Species: 64.67
UniProt: Q9BRX5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRX5 NP_001119601.1 216 24535 S195 C W E K G Q A S Q I T A S N L
Chimpanzee Pan troglodytes XP_511004 216 24530 S195 C W E K G Q A S Q I T A S N L
Rhesus Macaque Macaca mulatta XP_001101868 216 24490 S195 C W E K G Q A S Q I T A S N L
Dog Lupus familis XP_544380 216 24342 S195 C W E K G Q A S Q I T A S S L
Cat Felis silvestris
Mouse Mus musculus Q9CY94 216 24558 S195 S W E K G Q A S Q I T A S S L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507732 216 24152 S195 C W E K G Q A S Q I T A S S L
Chicken Gallus gallus XP_413991 214 23844 S193 C W E K G Q A S Q I T V S S L
Frog Xenopus laevis NP_001080618 210 23901 A189 S W E R G K A A Q I T A S N L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781737 212 24582 T188 S W E T R Q I T K I C T S D M
Poplar Tree Populus trichocarpa XP_002316214 184 20940 R164 M A A F K K W R M G G P R L Q
Maize Zea mays NP_001147271 194 21689 Q174 R V G G V R L Q K A S I L G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 94.4 N.A. 89.3 N.A. N.A. 81.9 75.4 72.6 N.A. N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 100 99.5 97.6 N.A. 94.4 N.A. N.A. 88.8 88.4 86.5 N.A. N.A. N.A. N.A. N.A. 67.5
P-Site Identity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. 93.3 86.6 73.3 N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 100 93.3 93.3 N.A. N.A. N.A. N.A. N.A. 60
Percent
Protein Identity: 25 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: 42.5 44.4 N.A. N.A. N.A. N.A.
P-Site Identity: 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 73 10 0 10 0 64 0 0 0 % A
% Cys: 55 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 82 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 73 0 0 0 0 10 10 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 82 0 10 0 0 0 % I
% Lys: 0 0 0 64 10 19 0 0 19 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 73 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 73 0 10 73 0 0 0 0 0 10 % Q
% Arg: 10 0 0 10 10 10 0 10 0 0 0 0 10 0 10 % R
% Ser: 28 0 0 0 0 0 0 64 0 0 10 0 82 37 0 % S
% Thr: 0 0 0 10 0 0 0 10 0 0 73 10 0 0 0 % T
% Val: 0 10 0 0 10 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 82 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _