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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GINS3 All Species: 22.42
Human Site: S21 Identified Species: 49.33
UniProt: Q9BRX5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BRX5 NP_001119601.1 216 24535 S21 G P E E N F L S L D D I L M S
Chimpanzee Pan troglodytes XP_511004 216 24530 S21 G P E E N F L S L D D I L M S
Rhesus Macaque Macaca mulatta XP_001101868 216 24490 S21 G P E E N F L S L D D I L M S
Dog Lupus familis XP_544380 216 24342 S21 G P E E N F L S L D D I L M S
Cat Felis silvestris
Mouse Mus musculus Q9CY94 216 24558 S21 G P E E N F L S L D D I L M S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507732 216 24152 S21 G P Q E N L L S L E D I L M S
Chicken Gallus gallus XP_413991 214 23844 L21 P E E N F L S L D D I L M S Q
Frog Xenopus laevis NP_001080618 210 23901 L21 R E E N F L S L E D L L M S Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781737 212 24582 N21 S D N Y Y D I N D I I A T H E
Poplar Tree Populus trichocarpa XP_002316214 184 20940
Maize Zea mays NP_001147271 194 21689 I10 G Y Y D I D D I L M E D E P I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 94.4 N.A. 89.3 N.A. N.A. 81.9 75.4 72.6 N.A. N.A. N.A. N.A. N.A. 42.1
Protein Similarity: 100 100 99.5 97.6 N.A. 94.4 N.A. N.A. 88.8 88.4 86.5 N.A. N.A. N.A. N.A. N.A. 67.5
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 80 13.3 13.3 N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 26.6 26.6 N.A. N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 25 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: 42.5 44.4 N.A. N.A. N.A. N.A.
P-Site Identity: 0 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 0 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 19 10 0 19 64 55 10 0 0 0 % D
% Glu: 0 19 64 55 0 0 0 0 10 10 10 0 10 0 10 % E
% Phe: 0 0 0 0 19 46 0 0 0 0 0 0 0 0 0 % F
% Gly: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 10 0 10 10 0 10 19 55 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 28 55 19 64 0 10 19 55 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 19 55 0 % M
% Asn: 0 0 10 19 55 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 55 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 19 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 0 19 55 0 0 0 0 0 19 55 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 10 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _