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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A3
All Species:
22.73
Human Site:
S125
Identified Species:
45.45
UniProt:
Q9BRY0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRY0
NP_653165.2
314
33601
S125
L
E
T
F
N
A
G
S
D
V
G
S
D
S
E
Chimpanzee
Pan troglodytes
XP_512260
411
43581
S222
L
E
T
F
N
A
G
S
D
V
G
S
D
S
E
Rhesus Macaque
Macaca mulatta
XP_001099216
314
33566
S125
L
E
T
F
N
A
G
S
D
V
G
S
D
S
E
Dog
Lupus familis
XP_854948
314
33784
S125
L
E
T
F
N
A
G
S
D
A
G
S
D
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99K24
317
33984
S125
L
E
T
F
N
A
G
S
D
A
G
S
D
S
E
Rat
Rattus norvegicus
Q5U1X7
317
33945
S125
L
E
T
F
N
A
G
S
D
A
G
S
D
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515297
246
26881
Y63
D
A
G
S
D
S
E
Y
E
S
P
F
I
G
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089979
307
34296
L120
M
S
E
E
T
T
P
L
L
S
G
N
A
N
S
Zebra Danio
Brachydanio rerio
P59889
302
32803
R114
L
S
C
T
E
G
H
R
N
E
E
T
A
P
L
Tiger Blowfish
Takifugu rubipres
Q6QQT1
302
33019
A114
L
N
C
K
E
M
R
A
T
H
E
E
R
T
T
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188747
346
37330
L130
E
Y
V
Q
L
Q
Q
L
E
N
E
T
D
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTH9
353
38294
N157
F
V
A
A
G
S
N
N
N
H
V
G
A
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.4
99.3
92
N.A.
83.2
83.5
N.A.
59.8
N.A.
33.4
32.7
34
N.A.
N.A.
N.A.
35.2
Protein Similarity:
100
76.4
99.3
95.5
N.A.
92.1
92.1
N.A.
69.4
N.A.
54.4
51.2
53.5
N.A.
N.A.
N.A.
52
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
20
N.A.
26.6
20
20
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
9
0
50
0
9
0
25
0
0
25
0
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
50
0
0
0
59
0
0
% D
% Glu:
9
50
9
9
17
0
9
0
17
9
25
9
0
0
50
% E
% Phe:
9
0
0
50
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
9
0
9
9
50
0
0
0
59
9
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
17
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
67
0
0
0
9
0
0
17
9
0
0
0
0
0
9
% L
% Met:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
50
0
9
9
17
9
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% P
% Gln:
0
0
0
9
0
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
0
0
0
9
0
0
% R
% Ser:
0
17
0
9
0
17
0
50
0
17
0
50
0
59
9
% S
% Thr:
0
0
50
9
9
9
0
0
9
0
0
17
0
17
17
% T
% Val:
0
9
9
0
0
0
0
0
0
25
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _