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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC35A5 All Species: 24.24
Human Site: S416 Identified Species: 38.1
UniProt: Q9BS91 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BS91 NP_060415.1 424 48500 S416 E R L T K P K S D E S D E D T
Chimpanzee Pan troglodytes XP_001155428 424 48493 S416 E R L T K P K S D E S D E D T
Rhesus Macaque Macaca mulatta XP_001104675 424 48302 S416 E R L T K P K S D E S D E D T
Dog Lupus familis XP_535741 425 48391 S416 E R L T K P K S D I E S D E D
Cat Felis silvestris
Mouse Mus musculus Q921R7 437 50097 S429 E R L T K L K S D D S D D D T
Rat Rattus norvegicus Q6AXR5 326 36060 P319 L Y G Y D P K P A G N P T K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517794 432 47441 S422 L E R L T K P S S D I D S D E
Chicken Gallus gallus XP_416587 427 48077 S418 E R L N K P S S D I D T D E D
Frog Xenopus laevis Q6DCG9 413 46959 E404 E K L T A A N E D S E T D E E
Zebra Danio Brachydanio rerio Q90X48 440 49526 T431 E R L T K A N T E S E S E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q93890 328 36427 S321 R L R G E I P S T K E A F C L
Sea Urchin Strong. purpuratus XP_793387 427 48683 E412 S V S E E L I E L T R M D E E
Poplar Tree Populus trichocarpa XP_002323564 305 33716 L298 I V S V S V Y L H S V G K M Q
Maize Zea mays NP_001149907 356 39391 I349 V S V Y L H S I G K L Q P Q K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_680766 352 38960 L345 V V S V S V Y L H S A G K L R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 91 N.A. 83.5 21.7 N.A. 66.9 69.5 58.4 55 N.A. N.A. N.A. 23.8 43
Protein Similarity: 100 99.7 98.5 94.1 N.A. 89 41.9 N.A. 78 79.8 74.7 72 N.A. N.A. N.A. 41 62.5
P-Site Identity: 100 100 100 60 N.A. 80 13.3 N.A. 20 46.6 26.6 40 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 100 73.3 N.A. 93.3 20 N.A. 26.6 60 46.6 60 N.A. N.A. N.A. 20 20
Percent
Protein Identity: 24.7 21.2 N.A. 20 N.A. N.A.
Protein Similarity: 41.9 38.2 N.A. 38.9 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 14 0 0 7 0 7 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 7 0 0 0 47 14 7 34 34 34 14 % D
% Glu: 54 7 0 7 14 0 0 14 7 20 27 0 27 34 27 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 7 7 0 0 0 0 7 7 0 14 0 0 0 % G
% His: 0 0 0 0 0 7 0 0 14 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 7 7 7 0 14 7 0 0 0 0 % I
% Lys: 0 7 0 0 47 7 40 0 0 14 0 0 14 7 7 % K
% Leu: 14 7 54 7 7 14 0 14 7 0 7 0 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % M
% Asn: 0 0 0 7 0 0 14 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 40 14 7 0 0 0 7 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 7 % Q
% Arg: 7 47 14 0 0 0 0 0 0 0 7 0 0 0 7 % R
% Ser: 7 7 20 0 14 0 14 54 7 27 27 14 7 0 0 % S
% Thr: 0 0 0 47 7 0 0 7 7 7 0 14 7 0 27 % T
% Val: 14 20 7 14 0 14 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 14 0 0 14 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _