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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTYH2 All Species: 15.15
Human Site: S457 Identified Species: 37.04
UniProt: Q9BSA4 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BSA4 NP_116035.5 534 58786 S457 L H S F C S Y S S G L G S Q T
Chimpanzee Pan troglodytes XP_001168124 534 58729 S457 L H R F C S Y S S G L G S Q T
Rhesus Macaque Macaca mulatta XP_001090041 507 55522 S431 H S F C S Y S S G L G S Q T S
Dog Lupus familis XP_533115 543 58844 S466 L R S F C S Y S S G L G S Q T
Cat Felis silvestris
Mouse Mus musculus Q3TH73 532 58989 S455 G Q L H S F C S Y S S G L G S
Rat Rattus norvegicus P0C5X8 450 49014 H374 L L H C R S L H K D Y G S A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511036 576 62281 W498 I C A V P R G W K Q L V V R W
Chicken Gallus gallus XP_414776 509 56810 Y433 R V H M P S L Y S C G S S Y G
Frog Xenopus laevis Q7ZWN9 534 59281 S457 L R S F C S Y S S S L G S Q A
Zebra Danio Brachydanio rerio Q6NUZ2 531 59517 S454 A Q V H S F C S Y S S S M G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 90.2 81 N.A. 82.5 35.2 N.A. 53.8 38.2 67 61 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.1 92.5 87.1 N.A. 91.1 51.8 N.A. 65.6 57.2 82.4 77.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 6.6 93.3 N.A. 13.3 26.6 N.A. 6.6 20 80 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 13.3 93.3 N.A. 20 26.6 N.A. 26.6 20 80 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 0 0 0 0 0 0 10 10 % A
% Cys: 0 10 0 20 40 0 20 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 40 0 20 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 10 0 10 30 20 60 0 20 10 % G
% His: 10 20 20 20 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 50 10 10 0 0 0 20 0 0 10 50 0 10 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 0 0 0 0 0 10 0 0 10 40 0 % Q
% Arg: 10 20 10 0 10 10 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 10 30 0 30 60 10 70 50 30 20 30 60 0 30 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 30 % T
% Val: 0 10 10 10 0 0 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 10 40 10 20 0 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _