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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM175
All Species:
24.55
Human Site:
S257
Identified Species:
77.14
UniProt:
Q9BSA9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSA9
NP_115702.1
504
55615
S257
F
D
L
H
E
P
L
S
K
E
R
V
E
A
F
Chimpanzee
Pan troglodytes
XP_001141076
504
55095
S257
F
D
L
H
E
P
L
S
K
E
R
V
E
A
F
Rhesus Macaque
Macaca mulatta
XP_001085173
403
44239
V184
L
D
I
C
E
D
N
V
P
D
P
K
E
V
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXY1
499
55560
S254
I
D
L
H
A
P
L
S
K
E
R
V
E
A
F
Rat
Rattus norvegicus
Q6AY05
499
55688
S254
I
D
L
H
A
P
L
S
K
E
R
V
E
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514176
499
56721
S255
F
N
I
H
E
P
L
S
K
E
R
V
E
A
F
Chicken
Gallus gallus
Q5ZKY0
501
56094
S257
F
Y
L
S
E
P
L
S
K
E
R
V
E
A
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A5PN43
520
58995
S274
Y
H
P
S
E
P
L
S
K
E
R
V
E
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.4
74
N.A.
N.A.
80.9
81.1
N.A.
62.9
61.3
N.A.
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.4
76.1
N.A.
N.A.
87.3
87.3
N.A.
78.1
74.4
N.A.
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
N.A.
N.A.
86.6
86.6
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
N.A.
N.A.
86.6
86.6
N.A.
100
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
25
0
0
0
0
0
0
0
0
88
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
63
0
0
0
13
0
0
0
13
0
0
0
0
0
% D
% Glu:
0
0
0
0
75
0
0
0
0
88
0
0
100
0
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
88
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
13
0
63
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
88
0
0
13
0
0
13
% K
% Leu:
13
0
63
0
0
0
88
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
88
0
0
13
0
13
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
88
0
0
0
0
% R
% Ser:
0
0
0
25
0
0
0
88
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
88
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _