KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDHD3
All Species:
18.18
Human Site:
S224
Identified Species:
36.36
UniProt:
Q9BSH5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSH5
NP_112496.1
251
28000
S224
L
D
P
V
V
R
D
S
V
P
K
E
H
I
L
Chimpanzee
Pan troglodytes
XP_001153430
251
28039
S224
L
D
P
V
V
R
D
S
V
P
K
E
H
I
L
Rhesus Macaque
Macaca mulatta
XP_001101765
251
28146
S224
L
D
P
V
V
R
D
S
V
P
K
E
H
I
L
Dog
Lupus familis
XP_538805
251
27906
S224
L
D
S
A
V
K
C
S
V
P
Q
E
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYW4
251
28009
S224
L
D
S
A
V
R
D
S
V
P
K
E
H
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507131
277
30788
A250
P
P
S
P
G
T
G
A
V
P
S
D
H
I
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5HZL9
244
27661
N218
T
P
P
K
L
Q
W
N
I
P
E
E
H
V
I
Zebra Danio
Brachydanio rerio
Q7T012
242
27185
D213
G
Y
L
L
N
R
K
D
G
Q
K
T
H
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94915
260
30095
G234
A
Y
L
V
K
K
Y
G
E
D
I
D
R
D
H
Honey Bee
Apis mellifera
XP_001122672
252
29412
D221
I
L
V
Q
H
N
N
D
V
I
D
E
K
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795618
241
27499
T214
Y
L
V
D
R
E
G
T
L
I
E
K
H
P
E
Poplar Tree
Populus trichocarpa
XP_002315800
254
28055
D222
V
G
D
D
L
K
A
D
K
Q
G
A
N
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96
78.8
N.A.
76.4
N.A.
N.A.
59.2
N.A.
49.4
41.4
N.A.
28.4
33.7
N.A.
35.4
Protein Similarity:
100
99.5
97.2
86.4
N.A.
86
N.A.
N.A.
68.5
N.A.
67.3
57.7
N.A.
48.4
47.2
N.A.
55.7
P-Site Identity:
100
100
100
60
N.A.
86.6
N.A.
N.A.
33.3
N.A.
26.6
20
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
N.A.
N.A.
46.6
N.A.
73.3
33.3
N.A.
20
33.3
N.A.
33.3
Percent
Protein Identity:
25.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
0
9
9
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
9
17
0
0
34
25
0
9
9
17
0
9
9
% D
% Glu:
0
0
0
0
0
9
0
0
9
0
17
59
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
9
0
17
9
9
0
9
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
75
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
9
17
9
0
0
42
17
% I
% Lys:
0
0
0
9
9
25
9
0
9
0
42
9
9
9
0
% K
% Leu:
42
17
17
9
17
0
0
0
9
0
0
0
0
17
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
9
9
0
0
0
0
9
0
0
% N
% Pro:
9
17
34
9
0
0
0
0
0
59
0
0
0
9
0
% P
% Gln:
0
0
0
9
0
9
0
0
0
17
9
0
0
0
0
% Q
% Arg:
0
0
0
0
9
42
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
25
0
0
0
0
42
0
0
9
0
0
0
0
% S
% Thr:
9
0
0
0
0
9
0
9
0
0
0
9
0
0
0
% T
% Val:
9
0
17
34
42
0
0
0
59
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _