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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEM1A
All Species:
18.79
Human Site:
S390
Identified Species:
34.44
UniProt:
Q9BSK4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSK4
NP_061178.1
669
73639
S390
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082251
669
73590
S390
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Dog
Lupus familis
XP_542150
673
73600
S394
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2G1
654
72071
S375
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Rat
Rattus norvegicus
Q4V890
654
72100
S375
G
P
S
H
P
D
T
S
Y
Y
I
R
Y
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521087
504
56174
Y251
R
C
I
H
L
W
K
Y
A
L
D
M
Q
Q
S
Chicken
Gallus gallus
Q5ZM55
627
70376
W367
F
E
Q
C
I
K
L
W
L
H
A
L
H
L
R
Frog
Xenopus laevis
Q2T9K6
617
68788
W361
F
K
R
C
I
N
L
W
K
Y
A
L
D
M
Q
Zebra Danio
Brachydanio rerio
Q6P9Z4
617
67993
L361
N
F
E
R
C
I
R
L
W
K
Y
A
L
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFD5
664
73767
Q377
Q
P
L
S
P
M
T
Q
S
S
L
L
S
F
A
Honey Bee
Apis mellifera
XP_392810
624
70030
D366
E
L
W
N
Y
A
L
D
M
Q
Q
S
M
L
E
Nematode Worm
Caenorhab. elegans
P17221
656
74268
H371
R
C
Y
D
L
W
K
H
A
L
E
L
Q
Q
K
Sea Urchin
Strong. purpuratus
XP_781836
644
72159
M378
L
W
M
Y
A
L
E
M
Q
Q
E
A
L
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
93.3
N.A.
89.6
89.3
N.A.
64.7
36.1
65
69.2
N.A.
38.2
46.4
32.5
50.2
Protein Similarity:
100
N.A.
99.8
94.5
N.A.
93.2
93.4
N.A.
69.8
55
77.5
78.7
N.A.
51.2
62.7
53.3
66.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
0
6.6
0
N.A.
20
0
0
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
13.3
13.3
6.6
N.A.
26.6
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
16
0
16
16
0
0
8
% A
% Cys:
0
16
0
16
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
39
0
8
0
0
8
0
8
8
0
% D
% Glu:
8
8
8
0
0
0
8
0
0
0
16
0
0
8
8
% E
% Phe:
16
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
39
% G
% His:
0
0
0
47
0
0
0
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
0
16
8
0
0
0
0
39
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
16
0
8
8
0
0
0
0
8
% K
% Leu:
8
8
8
0
16
8
24
8
8
16
8
31
16
16
0
% L
% Met:
0
0
8
0
0
8
0
8
8
0
0
8
8
8
8
% M
% Asn:
8
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
47
0
0
47
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
0
0
0
0
8
8
16
8
0
16
16
8
% Q
% Arg:
16
0
8
8
0
0
8
0
0
0
0
39
0
39
8
% R
% Ser:
0
0
39
8
0
0
0
39
8
8
0
8
8
0
8
% S
% Thr:
0
0
0
0
0
0
47
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
8
0
0
16
0
16
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
8
39
47
8
0
39
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _