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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FEM1A
All Species:
41.21
Human Site:
T217
Identified Species:
75.56
UniProt:
Q9BSK4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSK4
NP_061178.1
669
73639
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082251
669
73590
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Dog
Lupus familis
XP_542150
673
73600
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2G1
654
72071
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Rat
Rattus norvegicus
Q4V890
654
72100
T217
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521087
504
56174
A106
P
E
A
G
E
A
P
A
P
E
D
A
R
P
Q
Chicken
Gallus gallus
Q5ZM55
627
70376
T221
M
V
N
G
H
G
M
T
P
L
K
V
A
A
E
Frog
Xenopus laevis
Q2T9K6
617
68788
T216
E
K
D
G
Y
G
M
T
P
L
L
S
A
S
V
Zebra Danio
Brachydanio rerio
Q6P9Z4
617
67993
T216
E
R
D
G
Y
G
M
T
P
L
L
A
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFD5
664
73767
T216
D
V
D
Y
Y
G
M
T
P
L
L
A
A
S
V
Honey Bee
Apis mellifera
XP_392810
624
70030
S216
G
V
D
S
Y
G
M
S
P
L
L
T
A
A
V
Nematode Worm
Caenorhab. elegans
P17221
656
74268
D223
M
K
D
I
Q
G
V
D
P
L
M
G
A
A
L
Sea Urchin
Strong. purpuratus
XP_781836
644
72159
T228
D
T
D
A
Y
G
I
T
P
I
K
A
A
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
93.3
N.A.
89.6
89.3
N.A.
64.7
36.1
65
69.2
N.A.
38.2
46.4
32.5
50.2
Protein Similarity:
100
N.A.
99.8
94.5
N.A.
93.2
93.4
N.A.
69.8
55
77.5
78.7
N.A.
51.2
62.7
53.3
66.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
46.6
86.6
100
N.A.
80
60
33.3
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
66.6
100
100
N.A.
86.6
73.3
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
8
0
0
0
70
93
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
85
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
54
8
0
0
8
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
70
0
93
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
16
0
0
0
0
0
0
0
0
16
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
85
70
0
0
0
8
% L
% Met:
16
0
0
0
0
0
77
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
100
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
47
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
8
0
0
0
8
0
0
0
8
0
62
0
% S
% Thr:
0
8
0
0
0
0
0
77
0
0
0
8
0
0
0
% T
% Val:
0
24
0
0
0
0
8
0
0
0
0
8
0
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
77
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _