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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FEM1A All Species: 4.24
Human Site: T260 Identified Species: 7.78
UniProt: Q9BSK4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BSK4 NP_061178.1 669 73639 T260 L P Q E D P S T S Q G C A Q P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082251 669 73590 T260 L P Q E G P S T S Q G C A Q P
Dog Lupus familis XP_542150 673 73600 G264 S S A A A A P G P A G A Q P Q
Cat Felis silvestris
Mouse Mus musculus Q9Z2G1 654 72071 Q256 L P G E G S S Q V A G N H C S
Rat Rattus norvegicus Q4V890 654 72100 Q256 L P G E G S S Q M A G N H C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521087 504 56174 E138 E A A V E A L E L L G A T F V
Chicken Gallus gallus Q5ZM55 627 70376 L253 R R S R I E A L E L L G A S F
Frog Xenopus laevis Q2T9K6 617 68788 L248 K N E R I N A L E L L G A T F
Zebra Danio Brachydanio rerio Q6P9Z4 617 67993 L248 R E Q R I H A L E L L G A T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VFD5 664 73767 G252 I H A L E L L G A T Y V D R K
Honey Bee Apis mellifera XP_392810 624 70030 G253 I D A L E L L G A T Y V D K K
Nematode Worm Caenorhab. elegans P17221 656 74268 G258 R D A L K L L G S T L L D K K
Sea Urchin Strong. purpuratus XP_781836 644 72159 G263 I D A L E L V G A T F V D K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 93.3 N.A. 89.6 89.3 N.A. 64.7 36.1 65 69.2 N.A. 38.2 46.4 32.5 50.2
Protein Similarity: 100 N.A. 99.8 94.5 N.A. 93.2 93.4 N.A. 69.8 55 77.5 78.7 N.A. 51.2 62.7 53.3 66.3
P-Site Identity: 100 N.A. 93.3 6.6 N.A. 33.3 33.3 N.A. 6.6 6.6 6.6 13.3 N.A. 0 0 6.6 0
P-Site Similarity: 100 N.A. 93.3 6.6 N.A. 33.3 33.3 N.A. 13.3 13.3 20 20 N.A. 26.6 26.6 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 47 8 8 16 24 0 24 24 0 16 39 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 16 0 16 0 % C
% Asp: 0 24 0 0 8 0 0 0 0 0 0 0 31 0 0 % D
% Glu: 8 8 8 31 31 8 0 8 24 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 24 % F
% Gly: 0 0 16 0 24 0 0 39 0 0 47 24 0 0 0 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 0 16 0 0 % H
% Ile: 24 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 8 0 0 0 0 0 0 0 0 24 31 % K
% Leu: 31 0 0 31 0 31 31 24 8 31 31 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 0 16 0 0 0 % N
% Pro: 0 31 0 0 0 16 8 0 8 0 0 0 0 8 16 % P
% Gln: 0 0 24 0 0 0 0 16 0 16 0 0 8 16 8 % Q
% Arg: 24 8 0 24 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 8 8 0 0 16 31 0 24 0 0 0 0 8 16 % S
% Thr: 0 0 0 0 0 0 0 16 0 31 0 0 8 16 0 % T
% Val: 0 0 0 8 0 0 8 0 8 0 0 24 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _