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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RTKN All Species: 23.33
Human Site: S225 Identified Species: 42.78
UniProt: Q9BST9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BST9 NP_001015055.1 563 62667 S225 S S S L G R S S G R R V R A S
Chimpanzee Pan troglodytes XP_001157465 563 62576 S225 S S S L G R S S G R R V R A S
Rhesus Macaque Macaca mulatta XP_001108982 563 62606 S225 S S S L G R S S G R R V R A S
Dog Lupus familis XP_532998 564 62928 S225 S S S L G R S S G R R V R A S
Cat Felis silvestris
Mouse Mus musculus Q8C6B2 564 63022 S225 S S S L G R S S G K R V R A S
Rat Rattus norvegicus Q6V7V2 548 61135 S212 S S S L G R S S G K R V R A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510217 606 68399 E233 T L T L E S T E D S F R T H S
Chicken Gallus gallus XP_421541 873 96370 S466 K K L K T S L S K A T G K K L
Frog Xenopus laevis Q5XGX5 612 69089 A204 R N S I G K S A G K K F N S E
Zebra Danio Brachydanio rerio Q5XIZ9 642 72394 G222 R K L R S S F G R S S G R K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393113 433 50447 H103 A Y M V E L E H Q K K N M S L
Nematode Worm Caenorhab. elegans NP_001024370 515 57305 A186 L D Q T I S G A H Y N L L A K
Sea Urchin Strong. purpuratus XP_786885 585 65695 A255 R K L S A L S A S V G R R G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.2 92.5 N.A. 86.5 83.6 N.A. 39.1 27.8 40.2 38.7 N.A. N.A. 25.9 22.9 28.3
Protein Similarity: 100 99.6 98.5 95.7 N.A. 90.9 89.1 N.A. 56.4 43.2 57.1 54 N.A. N.A. 46 40.5 43.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 6.6 26.6 6.6 N.A. N.A. 0 6.6 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 13.3 73.3 6.6 N.A. N.A. 33.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 24 0 8 0 0 0 54 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 16 0 8 8 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 0 % F
% Gly: 0 0 0 0 54 0 8 8 54 0 8 16 0 8 0 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 24 0 8 0 8 0 0 8 31 16 0 8 16 8 % K
% Leu: 8 8 24 54 0 16 8 0 0 0 0 8 8 0 24 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 8 8 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 24 0 0 8 0 47 0 0 8 31 47 16 62 0 0 % R
% Ser: 47 47 54 8 8 31 62 54 8 16 8 0 0 16 62 % S
% Thr: 8 0 8 8 8 0 8 0 0 0 8 0 8 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 8 0 47 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _