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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTKN
All Species:
13.33
Human Site:
T478
Identified Species:
24.44
UniProt:
Q9BST9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BST9
NP_001015055.1
563
62667
T478
R
E
G
A
R
L
E
T
P
P
P
W
L
A
M
Chimpanzee
Pan troglodytes
XP_001157465
563
62576
T478
R
E
G
A
R
L
E
T
P
P
P
W
L
A
M
Rhesus Macaque
Macaca mulatta
XP_001108982
563
62606
T478
R
E
G
A
R
L
E
T
P
P
P
W
L
A
M
Dog
Lupus familis
XP_532998
564
62928
T478
R
E
G
T
R
L
E
T
P
P
P
W
L
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8C6B2
564
63022
P478
R
E
G
T
R
L
E
P
S
P
P
W
L
A
M
Rat
Rattus norvegicus
Q6V7V2
548
61135
E464
Q
R
E
G
T
R
L
E
P
P
P
P
W
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510217
606
68399
E521
F
D
K
E
N
F
W
E
K
A
G
V
A
Y
R
Chicken
Gallus gallus
XP_421541
873
96370
G719
R
K
I
E
K
S
D
G
E
F
L
L
C
Q
Q
Frog
Xenopus laevis
Q5XGX5
612
69089
G454
N
K
I
E
E
T
D
G
Q
F
L
I
G
P
Q
Zebra Danio
Brachydanio rerio
Q5XIZ9
642
72394
G475
N
K
I
E
E
T
N
G
R
F
L
I
G
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393113
433
50447
R349
N
V
T
D
N
E
K
R
D
V
I
E
L
Y
S
Nematode Worm
Caenorhab. elegans
NP_001024370
515
57305
Q431
A
K
V
I
D
F
F
Q
A
Q
S
P
K
P
S
Sea Urchin
Strong. purpuratus
XP_786885
585
65695
P501
E
N
V
F
Q
G
P
P
S
D
N
L
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
92.5
N.A.
86.5
83.6
N.A.
39.1
27.8
40.2
38.7
N.A.
N.A.
25.9
22.9
28.3
Protein Similarity:
100
99.6
98.5
95.7
N.A.
90.9
89.1
N.A.
56.4
43.2
57.1
54
N.A.
N.A.
46
40.5
43.9
P-Site Identity:
100
100
100
93.3
N.A.
80
20
N.A.
0
6.6
0
0
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
26.6
N.A.
6.6
26.6
13.3
6.6
N.A.
N.A.
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
24
0
0
0
0
8
8
0
0
8
39
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
8
8
0
16
0
8
8
0
0
0
0
0
% D
% Glu:
8
39
8
31
16
8
39
16
8
0
0
8
0
0
8
% E
% Phe:
8
0
0
8
0
16
8
0
0
24
0
0
0
0
0
% F
% Gly:
0
0
39
8
0
8
0
24
0
0
8
0
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
8
0
0
0
0
0
0
8
16
0
0
0
% I
% Lys:
0
31
8
0
8
0
8
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
39
8
0
0
0
24
16
47
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
39
% M
% Asn:
24
8
0
0
16
0
8
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
16
39
47
47
16
0
16
0
% P
% Gln:
8
0
0
0
8
0
0
8
8
8
0
0
0
16
16
% Q
% Arg:
47
8
0
0
39
8
0
8
8
0
0
0
8
0
16
% R
% Ser:
0
0
0
0
0
8
0
0
16
0
8
0
0
8
16
% S
% Thr:
0
0
8
16
8
16
0
31
0
0
0
0
0
0
0
% T
% Val:
0
8
16
0
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
39
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _